• Publications
  • Influence
Sox2 targets cyclinE, p27 and survivin to regulate androgen‐independent human prostate cancer cell proliferation and apoptosis
Sox2 is a major transcription factor and the transforming growth factor‐α (TGF‐α)/EGFR autocrine loop is a hallmark of prostate cancer progression. In this study, we have evaluated the effects andExpand
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Isolation of avian influenza virus (H9N2) from emu in China
This is the first reported isolation of avian influenza virus (AIV) from emu in China. An outbreak of AIV infection occurred at an emu farm that housed 40 four-month-old birds. Various degrees ofExpand
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Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport
  • Y. Bai, Lilin Ye, +5 authors X. Zhu
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 31 October 2011
IgG was traditionally thought to neutralize virions by blocking their attachment to or penetration into mucosal epithelial cells, a common site of exposure to viruses. However, we describe anExpand
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A five-year follow-up study of goiter and thyroid nodules in three regions with different iodine intakes in China
  • X. Yu, C. Fan, +22 authors W. Teng
  • Medicine
  • Journal of endocrinological investigation
  • 1 March 2008
Objective: The association between iodine status and the prevalence of goiter and thyroid nodules has been well established but the extent to which different iodine intake levels influence theExpand
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Prion Protein Participates in the Protection of Mice from Lipopolysaccharide Infection by Regulating the Inflammatory Process
Despite the overwhelming evidence of the involvement of prion protein (PrP) in prion disease pathogenesis, the normal functions of this cell surface glycoprotein remain unclear. Previously, we showedExpand
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Role of the Retromer Complex in Neurodegenerative Diseases
The retromer complex is a protein complex that plays a central role in endosomal trafficking. Retromer dysfunction has been linked to a growing number of neurological disorders. The process ofExpand
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Consecutive extreme visibility events in China during 1960–2009
Abstract Features of consecutive extreme visibility events, such as the annual maximum duration of consecutive good visibility (≥20 km) and bad visibility (
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The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages
The cellular prion protein (PrPC) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein on the cell surface. Previous studies have demonstrated contradictory roles for PrPC in connection withExpand
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Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt–Jakob Disease
Sporadic Creutzfeldt–Jakob disease (sCJD) is the most frequent fatal human prion disease with a rapid progression and unknown mechanism. The synaptic vesicle (SV) cycle pathway has been a hotExpand
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Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling
&NA; Prion diseases are a group of infectious neurodegenerative diseases characterized by multiple neuropathological hallmarks, including accumulation of PrPSc, synaptic damage, and neuronal death.Expand
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