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The unique evolution of neuropeptide genes in the silkworm Bombyx mori.
Identification of Ecdysis-Triggering Hormone from an Epitracheal Endocrine System
TLDR
Developing insects repeatedly shed their cuticle by means of a stereotyped behavior called ecdysis, thought to be initiated by the brain peptide eclosion hormone, which is described from the tobacco hornworm Manduca sexta.
Neuropeptide Receptor Transcriptome Reveals Unidentified Neuroendocrine Pathways
TLDR
The comprehensive cloning of neuropeptide G protein-coupled receptors from the silkworm, Bombyx mori, and systematic analyses of their expression confirm the effectiveness of a systematic analysis of the receptor transcriptome, not only in characterizing orphan receptors, but also in identifying novel players and hidden mechanisms in important biological processes.
Corazonin receptor signaling in ecdysis initiation.
TLDR
Findings support the role of corazonin signaling in initiation of the ecdysis behavioral sequence and propose a model for peptide-mediated interactions between Inka cells and the CNS underlying this process in insect development.
Central peptidergic ensembles associated with organization of an innate behavior
TLDR
In insights into how innate, centrally patterned behaviors can be orchestrated via recruitment of peptide cotransmitter neurons, the ETH receptor (ETHR) gene in the moth Manduca sexta is identified.
Peptidergic innervation and endocrine cells of insect midgut
TLDR
Investigations on Galleria revealed that the gut innervation persists during midgut reconstruction in the course of metamorphosis, and all insects seem to contain antigens that can be detected with antisera to pancreatic polypeptide, FMRFamide, enkephalins, and vasopressins.
Accumulation of neuropeptides in the cerebral neurosecretory system of Manduca sexta Larvae Parasitized by the Braconid Wasp Cotesia congregata
TLDR
The results suggest that accumulation of the neuropeptides is associated with developmental arrest of parasitized larvae and illustrate the potential value of using parasitized M. sexta larvae as a model for studying the mechanisms governing the rates of neuropepeptide expression, processing, packaging, and release.
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