• Publications
  • Influence
Oxygen Distribution and Consumption within the Retina in Vascularised and Avascular Retinas and in Animal Models of Retinal Disease
  • D. Yu, S. Cringle
  • Medicine, Biology
  • Progress in Retinal and Eye Research
  • 1 March 2001
Maintenance of an adequate oxygen supply to the retina is critical for retinal function. In species with vascularised retinas, such as man, oxygen is delivered to the retina via a combination of theExpand
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Optic disc movement with variations in intraocular and cerebrospinal fluid pressure.
PURPOSE To determine the effect of intraocular pressure (IOP) and cerebrospinal fluid pressure (CSFP) on optic disc movement and lamina cribrosa displacement using confocal scanning laser tomographyExpand
  • 159
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  • PDF
Retinal degeneration and local oxygen metabolism.
Vision loss due to various forms of outer retinal degeneration remains a major problem in clinical ophthalmology. Most retinal degenerations are precipitated by genetic mutations affecting theExpand
  • 243
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Retinal ganglion cells: Energetics, compartmentation, axonal transport, cytoskeletons and vulnerability
Retinal ganglion cells (RGCs) are specialized projection neurons that relay an immense amount of visual information from the retina to the brain. RGC signal inputs are collected by dendrites andExpand
  • 107
  • 8
Quantitative morphometry of perifoveal capillary networks in the human retina.
PURPOSE To quantify the distribution and morphometric characteristics of capillary networks in the human perifovea. To determine correlations between the location of neuronal subcellular compartmentsExpand
  • 124
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Model of endothelin-1-induced chronic optic neuropathy in rat.
PURPOSE To describe a model of chronic endothelin (ET)-1 administration to the optic nerve and evaluate its effect on retinal ganglion cell (RGC) and axon survival in rat. METHODS Osmotic minipumpsExpand
  • 146
  • 6
Photoreceptor death, trophic factor expression, retinal oxygen status, and photoreceptor function in the P23H rat.
PURPOSE To relate the oxygen environment of the retina to photoreceptor stability, protection, and function in the P23H rat. METHODS Heterozygote P23H-3 (Line 3) rats were studied. PhotoreceptorExpand
  • 142
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Intraretinal oxygen consumption in the rat in vivo.
PURPOSE To make the first quantitative assessment of the rate of oxygen consumption in high oxygen-consuming layers of both the outer and inner retina of the rat in vivo. METHODS Oxygen-sensitiveExpand
  • 128
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Microstructure and network organization of the microvasculature in the human macula.
PURPOSE To characterize the topography and cellular structure of the macular microvasculature using a recently developed technique of arterial cannulation, perfusion, fixation, and staining of humanExpand
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Effect of triamcinolone acetonide on vascular endothelial growth factor and occludin levels in branch retinal vein occlusion.
PURPOSE To investigate the molecular mechanism by which triamcinolone acetonide (TA) may reduce edema in a porcine model of branch retinal vein occlusion (BRVO). DESIGN Animal study. METHOD AfterExpand
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