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Structure of Trichamide, a Cyclic Peptide from the Bloom-Forming Cyanobacterium Trichodesmium erythraeum, Predicted from the Genome Sequence
ABSTRACT A gene cluster for the biosynthesis of a new small cyclic peptide, dubbed trichamide, was discovered in the genome of the global, bloom-forming marine cyanobacterium Trichodesmium erythraeumExpand
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Theonellamide G, a Potent Antifungal and Cytotoxic Bicyclic Glycopeptide from the Red Sea Marine Sponge Theonella swinhoei
In our search for bioactive metabolites from marine organisms, we have investigated the polar fraction of the organic extract of the Red Sea sponge Theonella swinhoei. Successive chromatographicExpand
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Penicillivinacine, antimigratory diketopiperazine alkaloid from the marine-derived fungus Penicillium vinaceum
Abstract In the course of our ongoing search for biologically active compounds from marine-derived fungi, the organic extract of the marine-derived fungus Penicillium vinaceum species wasExpand
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New ursane-type triterpenes from the root bark of Calotropis procera
Abstract As a part of our continuing interest in identifying anticancer drug leads from natural sources, we have investigated the in vitro growth inhibitory effects of the hexane fraction of the rootExpand
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Burkholdines 1097 and 1229, potent antifungal peptides from Burkholderia ambifaria 2.2N.
Potent antifungal cyclic lipopeptides, burkholdines (Bk), were isolated from a culture of Burkholderia ambifaria 2.2N. Bk-1229 (1) and Bk-1097 (2) are octapeptides comprised of nonproteinogenic aminoExpand
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Hepatoprotective effect of flavonol glycosides rich fraction from egyptianVicia calcarata desf. Against CCI4-induced liver damage in rats
The hepatoprotective activity of flavonol glycosides rich fraction, (F-2), prepared from 70% alcohol extract of the aerial parts ofV. calcarata Desf., was evaluated in a rat model with a liver injuryExpand
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Identification and Bioactivity of Compounds from the Fungus Penicillium sp. CYE-87 Isolated from a Marine Tunicate
In the course of our continuous interest in identifying bioactive compounds from marine microbes, we have investigated a tunicate-derived fungus, Penicillium sp. CYE-87. A new compound with theExpand
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Bioactive alkaloids from the Red Sea marine Verongid sponge Pseudoceratina arabica
Abstract Three new dibrominated alkaloids, ceratinines F–H (2–4), together with the known compounds molokia'iamine (1), psammaplysin A (5), ceratinamide A (6), 19-hydroxyceratinamide A (7),Expand
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Calotroposides H–N, new cytotoxic oxypregnane oligoglycosides from the root bark of Calotropis procera
As a part of our continuing interest in identifying anticancer drug leads from natural sources, we have investigated the n-BuOH fraction of the root bark of Calotropis procera (Ait) R. Br. Seven newExpand
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New compounds from the Red Sea marine sponge Echinoclathria gibbosa
Three new compounds; β-sitosterol-3-O-(3Z)-pentacosenoate (1), 5α-pregna-3β-acetoxy-12β,16β-diol-20-one (2), and echinoclathriamideExpand
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