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  • Influence
Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change.
BACKGROUND Mephedrone is a synthetic cathinone that is commonly used as a recreational drug among those who attend nightclubs. There have been increasing reports of toxicity associated with its useExpand
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2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death
Abstract2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects. DNP is sold mostly over theExpand
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Novel psychoactive substances: classification, pharmacology and toxicology.
Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances,Expand
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Hyperglycaemia is associated with poor outcomes in patients admitted to hospital with acute exacerbations of chronic obstructive pulmonary disease
Background: Hyperglycaemia is associated with poor outcomes from pneumonia, myocardial infarction and stroke, but the effect of blood glucose on outcomes from acute exacerbations of chronicExpand
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Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine
PurposeLong-term regular use of ketamine has been reported to be associated with severe symptomatic urinary tract problems. Methoxetamine, an arylcyclohexylamine derivative of ketamine, is marketedExpand
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Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis.
In animals, glucose concentrations are 3-20 times lower in lung lining fluid than in plasma. In humans, glucose concentrations are normally low (<1 mmol/l) in nasal and bronchial fluid, but they areExpand
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Limited use of novel psychoactive substances in South London nightclubs.
BACKGROUND There has been significant media interest in the use of novel psychoactive substances (also known as 'legal highs') and reports in the medical literature of toxicity associated with theirExpand
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The epidemiology and patterns of acute and chronic toxicity associated with recreational ketamine use
Ketamine was originally synthesised for use as a dissociative anaesthetic, and it remains widely used legitimately for this indication. However, there is increasing evidence of non-medicalExpand
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Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.
γ-Aminobutyric acid (GABA)-analogue medications, including gabapentin and pregabalin, are recommended first-line treatments for neuropathic pain in the UK [1], and pregabalin has been used in theExpand
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Effect of the UK’s revised paracetamol poisoning management guidelines on admissions, adverse reactions and costs of treatment
Aims In September 2012 the UK’s Commission on Human Medicines (CHM) recommended changes in the management of paracetamol poisoning: use of a single ‘100 mg l−1’ nomogram treatment line, ceasing riskExpand
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