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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity
TLDR
The aim of this study is to study the concurrent validity of the HarP toward local protocols, and its major sources of variance. Expand
Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol
TLDR
This work aims to produce a set of HarP labels for the proper training and certification of tracers and algorithms. Expand
Association of Structural Global Brain Network Properties with Intelligence in Normal Aging
TLDR
First evidence of an association between global structural brain network properties and general intelligence in advanced elderly is provided, suggesting that general intelligence and global properties of structural brain networks may not be generally associated in cognitively healthy elderly. Expand
Hippocampal atrophy as a surrogate of neuronal involvement in Fabry disease
TLDR
In this young to middle-aged Fabry cohort the hippocampus degeneration was functionally compensated without memory impairment and, in concert with the individual WML-load, predict subsequent cognitive decline. Expand
Differential associations of age with volume and microstructure of hippocampal subfields in healthy older adults
TLDR
Investigation of the associations between age and volume as well as microstructural integrity of hippocampal subfields using a 3D surface mapping approach indicates that age‐related volumetric and microStructural alterations within hippocampalSubfields provide complementary information and reflect different age-related processes. Expand
Altered whole-brain white matter networks in preclinical Alzheimer's disease
TLDR
An impairment of WM networks in preclinical AD is suggested that is detectable while other structural imaging markers do not yet indicate incipient neurodegeneration, and these findings are specific to WM networks and cannot be explained by other surrogates of global WM integrity. Expand
State dependent posterior hippocampal volume increases in patients with major depressive disorder.
TLDR
Patients with MDD showed selective increases in posterior hippocampal volumes which were not correlated to the degree of functional restitution, but might constitute a surrogate parameter of neuroplasticity taking place during antidepressant therapy which might be predicted by executive functioning at baseline. Expand
Age‐related increases in stroop interference: Delineation of general slowing based on behavioral and white matter analyses
TLDR
Results suggest that cognitive inhibition, as measured by Stroop task, is a qualitatively distinct cognitive process that declines with age, and expands the knowledge of the neural basis of Stroop interference. Expand
Association of basal forebrain volumes and cognition in normal aging
TLDR
Since general intelligence is known to attenuate the degree of age-associated cognitive decline and the risk of developing late-onset AD, the BFCS might, besides the specific contribution to the pathophysiology in AD, constitute a mechanism of brain resilience in normal aging. Expand
Structural integrity of the corpus callosum predicts long‐term transfer of fluid intelligence‐related training gains in normal aging
TLDR
Surprisingly, age was not directly associated with transfer in this study which could be explained by the multi‐dependency of the structural integrity (modulating factors beside age, e.g. genetics). Expand
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