• Publications
  • Influence
Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb
While adult-born neurons in the olfactory bulb (OB) and the dentate gyrus (DG) subregion of the hippocampus have fundamentally different properties, they may have more in common than meets the eye.Expand
  • 453
  • 25
  • PDF
ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
Reversing Decline? Apolipoprotein E (apoE) normally helps in the clearance of β-amyloid from the brain, a process that is compromised in Alzheimer's disease. Cramer et al. (p. 1503, published onlineExpand
  • 833
  • 21
  • PDF
Dynamics of Active Sensing and perceptual selection
Most sensory processing is active, and largely determined by motor/attentional sampling routines; second, owing to rhythmicity in the motor routine, as well as to its entrainment of ambient rhythms, sensory inflow tends to be rhythmic; third, attentional manipulation of rhythms in sensory pathways is instrumental to perceptual selection. Expand
  • 424
  • 17
Habituation of odor responses in the rat anterior piriform cortex.
  • D. Wilson
  • Biology, Medicine
  • Journal of neurophysiology
  • 1 March 1998
Simultaneous recordings of main olfactory bulb (MOB) and anterior piriform cortex (aPCX) neuron responses to repeated and prolonged odor pulses were examined in freely breathing, urethan-anesthetizedExpand
  • 202
  • 16
  • PDF
Cortical Processing of Odor Objects
Natural odors, generally composed of many monomolecular components, are analyzed by peripheral receptors into component features and translated into spatiotemporal patterns of neural activity in theExpand
  • 310
  • 15
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
Autophagy, a major degradative pathway for proteins and organelles, is essential for survival of mature neurons. Extensive autophagic-lysosomal pathology in Alzheimer's disease brain contributes toExpand
  • 351
  • 14
  • PDF
Olfactory Dysfunction Correlates with Amyloid-β Burden in an Alzheimer's Disease Mouse Model
Alzheimer's disease often results in impaired olfactory perceptual acuity—a potential biomarker of the disorder. However, the usefulness of olfactory screens to serve as informative indicators ofExpand
  • 217
  • 14
Spatial and Temporal Distribution of Odorant-Evoked Activity in the Piriform Cortex
Despite a remarkably precise spatial representation of odorant stimuli in the early stages of olfactory processing, the projections to the olfactory (piriform) cortex are more diffuse and showExpand
  • 168
  • 14
  • PDF
Learning to Smell: Olfactory Perception from Neurobiology to Behavior
Written by a neurobiologist and a psychologist, this volume presents a new theory of olfactory perception. Drawing on research in neuroscience, physiology, and ethology, Donald A. Wilson and RichardExpand
  • 205
  • 13
Neurobiology of associative learning in the neonate: early olfactory learning.
Mammalian neonates have been simultaneously described as having particularly poor memory, as evidenced by infantile amnesia, and as being particularly excellent learners with unusually plasticExpand
  • 210
  • 11