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Control of cell behavior during vertebrate development by Slug, a zinc finger gene.
Slug, a vertebrate gene encoding a zinc finger protein of the Snail family, is expressed in the neural crest and in mesodermal cells emigrating from the primitive streak. Early chick embryos wereExpand
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Expression pattern of the mouse T gene and its role in mesoderm formation
FORMATION of mesoderm is a crucial event in vertebrate development, establishing many of the important features of the body1–4. Recent studies have implicated molecules that are similar to growthExpand
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Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis
We report that the many Eph-related receptor tyrosine kinases, and their numerous membrane-bound ligands, can each be grouped into only two major specificity subclasses. Receptors in a given subclassExpand
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In situ hybridization: a practical approach
"In situ" hybridization is used to reveal the location of specific nucleic acids sequences on chromosomes or in tissues. Visualization of the location of genes on chromosomes or of specific mRNAs orExpand
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Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse
The process of segmentation, in which repeated homologous structures are generated along the anterior–posterior axis of the embryo is a widespread mechanism in animal development. In vertebrates,Expand
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The structure and expression of the Xenopus Krox-20 gene: conserved and divergent patterns of expression in rhombomeres and neural crest
Recent studies in the chick have indicated that rhombomeres (r) are segments that underlie the patterning of hindbrain nerves. These segments may also be important for the specification of branchialExpand
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In situ hybridization analysis of chick embryos in whole mount and tissue sections.
Publisher Summary This chapter presents in situ hybridization analysis of chick embryos in whole-mount and tissue sections. Detection of the temporal and spatial regulation of gene expression inExpand
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The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells
BACKGROUND During vertebrate head development, neural crest cells migrate from hindbrain segments to specific branchial arches, where they differentiate into distinct patterns of skeletal structures.Expand
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Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts.
13 paginas.-- En: Guide to Techniques in Mouse Development, Edited by: Paul M. Wassarman, Melvin L. DePamphilis; ISBN: 978-0-12-182126-5.
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Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain
The vertebrate hindbrain develops in a segmental pattern, with distinctive groups of neurons originating from different segments. We report here that members of the Hox-2 cluster of murine homoeoboxExpand
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