• Publications
  • Influence
Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability
  • D. Wheatley
  • Medicine
  • Journal of psychopharmacology
  • 1 July 2005
TLDR
There is a need for longer-term controlled studies with some of these compounds (particularly valerian) and aromatherapy constitutes a tantalising possibility, but how practical a form of treatment this may be remains to be determined. Expand
LI 160, an extract of St. John's wort, versus amitriptyline in mildly to moderately depressed outpatients--a controlled 6-week clinical trial.
  • D. Wheatley
  • Medicine, Psychology
  • Pharmacopsychiatry
  • 1 September 1997
TLDR
LI 160 was clearly superior to amitriptyline, particularly in relation to anticholinergic and Central Nervous System adverse events, and could confer an advantage in improving compliance for antidepressant pharmacotherapy. Expand
Mirtazapine: efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder. Mirtazapine-Fluoxetine Study Group.
TLDR
It was found that mirtazapine was as well tolerated as fluoxetine and significantly more effective after 3 and 4 weeks of therapy. Expand
Clinical sleep patterns in human immune virus infection
TLDR
The results showed that the HIV patients had significantly more sleep disturbance than the matched controls, with resultant implications for improving quality of life in this respect. Expand
Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial.
  • D. Wheatley, C. Bass
  • Psychology, Medicine
  • The British journal of psychiatry : the journal…
  • 1 February 1991
TLDR
Comprehensive lifestyle changes may be able to bring about regression of even severe coronary atherosclerosis after only 1 year, without use of lipid-lowering drugs. Expand
Triple‐blind, placebo‐controlled trial of Ginkgo biloba in sexual dysfunction due to antidepressant drugs
  • D. Wheatley
  • Medicine, Psychology
  • Human psychopharmacology
  • 1 December 2004
TLDR
A triple‐blind, randomized, placebo‐controlled, trial of Ginkgo biloba 240 mg daily was carried out with some spectacular individual responses in both groups, but no statistically significant differences, and no differences in side‐effects. Expand
Hypericum in seasonal affective disorder (SAD).
  • D. Wheatley
  • Medicine
  • Current medical research and opinion
  • 1999
TLDR
There were no significant between-group differences on any measure except that improvement in sleep was greater in the Kira + light group, and Hypericum would appear to be an effective treatment for SAD. Expand
Depression and the menopause.
  • D. Wheatley
  • Psychology, Medicine
  • The British journal of psychiatry : the journal…
  • 1 March 1991
Psychiatric aspects of hypertension.
TLDR
The survey showed that anxiety symptoms are relatively common and symptoms of depression and anger-hostility are not; although there were no significant differences between the hypertensive patients and their control groups, demonstrating that psychological factors may play a part in the aetiology of hypertension. Expand
Influence of doctors' and patients' attitudes in the treatment of neurotic illness.
TLDR
In a double-blind trial comparing chlordiazepoxide to amylobarbitone in chronic anxiety, 70 general practitioners treated 134 patients and it was not found that the response to treatment was influenced by the attitude of either doctors or patients at any stage of the trials. Expand
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