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Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery.
A novel water-soluble lipopolymer was synthesized by linking cholesteryl chloroformate to the secondary amino groups of branched poly(ethylenimine) (PEI) of 1,800 and 10,000 Da. Conjugation throughExpand
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Lipopolysaccharide‐inactivating activity of neutrophils is due to lactoferrin
Neutrophils can inactivate lipopolysaccharide (LPS), thereby blocking the ability of LPS to prime fresh neutrophils for enhanced fMLP‐triggered release of superoxide. Here we show that inactivationExpand
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Feasibility of Using a Bone-Targeted, Macromolecular Delivery System Coupled with Prostaglandin E1 to Promote Bone Formation in Aged, Estrogen-Deficient Rats
PurposeMacromolecular delivery systems have therapeutic uses because of their ability to deliver and release drugs to specific tissues. The uptake and localization of HPMA copolymers using Asp8 asExpand
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Sintered Microsphere Scaffolds for Controlled Release and Tissue Engineering
Scaffolds are an essential component in tissue engineering, as they provide a three-dimensional niche for cell residence and tissue regeneration (1). In recent decades, further incorporation ofExpand
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