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Influence of single-stranded DNA-binding protein on recA induction in Escherichia coli.
- R. R. Meyer, D. Voegele, S. M. Ruben, D. Rein, J. Trela
- Biology, Medicine
- Mutation research
- 1 June 1982
Two ssb mutants of Escherichia coli, which carry a lesion in the single-strand DNA-binding protein (SSB), are sensitive to UV-irradiation. We have investigated the influence of SSB on the "SOS"… Expand
In vitro--in vivo correlation, a time scaling problem? Basic techniques for testing equivalence.
Practical application of the concept of mean times in biopharmaceutics.
- D. Voegele
- Methods and findings in experimental and clinical…
- 1 October 1984
The "concept of mean times" (1) in combination with the "method of moments" (3, 4) provides a practical basis for handling biopharmaceutical problems. This holds for in vitro, in vitro/in vivo and in… Expand
Surgical Clipping of Difficult Intracranial Aneurysms Using Deep Hypothermia and Total Circulatory Arrest
- A. Pacult, G. Gratzick, D. Voegele, C. Worthington, G. Quinn, T. Utsey
- Southern medical journal
- 1 August 1993
Intracranial aneurysms often present a challenging problem for the neurosurgeon. A variety of techniques have been developed to deal with these lesions. Several subspecialists are frequently involved… Expand
In vivo relevance of a controlled oral release system of Molsidomine
Correlation of pharmacodynamic activity and pharmacokinetics of Molsidomine
With Molsidomine (M.) [Corvaton®] a double blind cross-over study in patients with coronary heart disease was performed. 2 mg M. (s. l.) reduced the ST-segment-depression and increased workload… Expand
[Release, absorption and elimination of theophylline from fast and slowly released oral formulations].
Each 2 tablets of four tablet formulations with 150 mg theophylline were administered to 6 and 5 volunteers, respectively, as single oral dose. 8 volunteers received 256 mg theophylline as a solution… Expand