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Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries.
Increased cardiovascular risk after mercury exposure has been described, but the underlying mechanisms are not well explored. We analyzed the effects of chronic exposure to low mercury concentrationsExpand
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Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension
Regular physical activity is an effective non‐pharmacological therapy for prevention and control of hypertension. We investigated the effects of aerobic exercise training in vascular remodelling andExpand
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Vasorelaxant effects of eugenol on rat thoracic aorta.
Eugenol is a natural pungent substance and the main component of clove oil, with vasorelaxant action. To elucidate some of the possible mechanisms involved in this action isometric tension wasExpand
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Effects of mercury on the isolated heart muscle are prevented by DTT and cysteine.
The protective effects of dithiothreitol (DTT, 50 microM) and cysteine (CYS, 100 microM) against toxic effects of HgCl2 (1, 2.5, 5, and 10 microM) were studied in isolated, isometrically contractingExpand
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Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery
Mercury is an environmental pollutant that reduces nitric oxide (NO) bioavailability and increases oxidative stress, having a close link with cardiovascular diseases, as carotid atherosclerosis,Expand
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Mesenteric Resistance Arteries in Type 2 Diabetic db/db Mice Undergo Outward Remodeling
Objective Resistance vessel remodeling is controlled by myriad of hemodynamic and neurohormonal factors. This study characterized structural and molecular remodeling in mesenteric resistance arteriesExpand
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Tributyltin contributes in reducing the vascular reactivity to phenylephrine in isolated aortic rings from female rats.
Organotin compounds such as tributyltin (TBT) are used as antifouling paints by shipping companies. TBT inhibits the aromatase responsible for the transformation of testosterone into estrogen. OurExpand
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Apocynin Prevents Vascular Effects Caused by Chronic Exposure to Low Concentrations of Mercury
Mercury increases the risk of cardiovascular disease and oxidative stress and alters vascular reactivity. This metal elicits endothelial dysfunction causing decreased NO bioavailability via increasedExpand
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MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways.
Chronic exposure to low lead concentration produces hypertension; however, the underlying mechanisms remain unclear. We analyzed the role of oxidative stress, cyclooxygenase-2-dependent pathways andExpand
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Ambulatory blood pressure monitoring in normotensive individuals undergoing two single exercise sessions: resistive exercise training and aerobic exercise training.
OBJECTIVE To assess the influence of 2 single exercise sessions on blood pressure in sedentary normotensive individuals: one of resistive exercise training (circuit weight training) and the other ofExpand
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