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Direct activation and temporal response properties of rabbit retinal ganglion cells following subretinal stimulation.
In the last decade several groups have been developing vision prostheses to restore visual perception to the profoundly blind. Despite some promising results from human trials, further understandingExpand
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Current steering in retinal stimulation via a quasimonopolar stimulation paradigm.
PURPOSE Research to restore some degree of vision to patients suffering from retinal degeneration is becoming increasingly more promising. Several groups have chosen electrical stimulation of theExpand
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Closed-Loop Efficient Searching of Optimal Electrical Stimulation Parameters for Preferential Excitation of Retinal Ganglion Cells
The ability for visual prostheses to preferentially activate functionally-distinct retinal ganglion cells (RGCs) is important for improving visual perception. This study investigates the use of highExpand
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Responses of Retinal Ganglion Cells to Extracellular Electrical Stimulation, from Single Cell to Population: Model-Based Analysis
Retinal ganglion cells (RGCs), which survive in large numbers following neurodegenerative diseases, could be stimulated with extracellular electric pulses to elicit artificial percepts. How do theExpand
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Direct activation of retinal ganglion cells with subretinal stimulation
We demonstrate that with appropriate stimulation strength 25 µm electrodes placed subretinally can reliably activate RGCs directly for all pulse widths tested (0.1 – 5.0ms). Expand
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Frequency-dependent reduction of voltage-gated sodium current modulates retinal ganglion cell response rate to electrical stimulation.
The ability to elicit visual percepts through electrical stimulation of the retina has prompted numerous investigations examining the feasibility of restoring sight to the blind. Expand
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Selective activation of ON and OFF retinal ganglion cells to high-frequency electrical stimulation: A computational modeling study
In this study, ON and OFF retinal ganglion cell (RGC) models based on accurate biophysics and realistic representations of cell morphologies were used to understand how these cells selectively respond to high-frequency electrical stimulation (HFS). Expand
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A wearable real-time image processor for a vision prosthesis
This paper presents a wearable image processor for use as the external module of a vision prosthesis. Expand
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Responses of starburst amacrine cells to prosthetic stimulation of the retina
This study analyzed the responses of one identified type of amacrine cells (the SACs) following subretinal electrical stimulation with cathodic–first biphasic stimulus. Expand
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Discrete cortical responses from multi-site supra-choroidal electrical stimulation in the feline retina
We investigate whether discrete, cortical activity patterns can be elicited via electrical stimulation of a feline retina using a custom, 14 channel, silicone rubber and Pt electrode array arranged in two hexagons comprising seven electrodes. Expand
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