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Interleukin‐17 and interleukin‐23: importance in the pathogenesis of lung impairment in patients with systemic sclerosis
T cell abnormalities with a focus on Th17 cells have been associated with the pathogenesis of systemic sclerosis (SSc) and interstitial lung disease (ILD). The aim of this study was to evaluate serumExpand
Circulating adipokines and organ involvement in patients with systemic sclerosis.
TLDR
Serum adiponectin should be further investigated as a candidate for SSc activity marker and resistin may play a role in ulcer development in SSc patients. Expand
Levels of EGF and VEGF in patients with primary and secondary Sjögren's syndrome.
TLDR
Saliva is more sensitive for the detection of EGF and VEGF than serum, but salivary levels of those proteins are not representative for SS. Expand
Salivary levels and immunohistochemical expression of selected angiogenic factors in benign and malignant parotid gland tumours
TLDR
The increased salivary VEGF reflects changes in affected parotid glands, but it cannot be used as a prognostic and differentiative factor forParotid tumours. Expand
Role of CYP1A1 in the biological activity of methylated resveratrol analogue, 3,4,5,4'-tetramethoxystilbene (DMU-212) in ovarian cancer A-2780 and non-cancerous HOSE cells.
TLDR
It is found that CYP1A1 is the major enzyme of CYP 1 family involved in the metabolic activation of DMU-212 and the level of this enzyme is contrary to other authors' suggestions. Expand
miRNA and Other Non-Coding RNAs as Promising Diagnostic Markers
TLDR
Detecting ncRNAs in biological fluids has opened a new field in Clinical Chemistry utilizing them as biomarkers of diseases or prognostic markers for different pathological conditions, according to their size and function. Expand
Blood serum levels of amino-terminal pro-C-type natriuretic peptide in patients with rheumatoid arthritis.
TLDR
Serum concentration of NT-proCNP reflecting serum CNP level is likely secondary to the activation of endothelium, and the results of this study encourage to further studies over the role of CNP in the pathogenesis of RA. Expand
Quantitative analysis of elastase and cathepsin G mRNA levels in peripheral blood CD14(+) cells from patients with rheumatoid arthritis.
TLDR
It is suggested that in rheumatoid arthritis, peripheral blood CD14(+) cells express serine protease mRNA as a result of systemic mechanisms probably related to inflammation/cytokines before entering inflamed joints. Expand
Expression of VEGF₁₆₅b, VEGFR1, VEGFR2 and CD34 in benign and malignant tumors of parotid glands.
TLDR
The correlation between VEGF165b and VEGFR2 in mixed tumors suggests the existence of an additional antiangiogenic pathway in poorly vascularized mixed tumors. Expand
Serum microRNAs in male subfertility—biomarkers and a potential pathogenetic link to metabolic syndrome
TLDR
None of the four miRNAs analyzed was associated both with male subfertility and MetS components, and the ability of miR-155-5p and mi-200c-3p to identify subfertile men was partly overruled by the presence of metabolic disturbances. Expand
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