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Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy
TLDR
Preliminary data suggest that a type 2 cytokine profile may be associated with normal human pregnancy, whereas the lack of a dominant type 1 cytokineprofile may be indicative of a pathologic pregnancy. Expand
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G: a possible role in the resistance to HIV of HIV-exposed seronegative individuals.
TLDR
Higher APOBEC3G expression correlated with a reduced susceptibility of PBMCs to in vitro infection with the HIV-1(Ba-L) R5 strain, indicating that this protein could be important in modulating in vivo susceptibility to sexually transmitted HIV infection. Expand
Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the “COPA” pilot randomized trial
TLDR
Dietary supplementation with a prebiotic oligosaccharide mixture results in improvement of the gut microbiota composition, reduction of sCD14, CD4+ T-cell activation (CD25), and improved NK cell activity in HAART-naive HIV-infected individuals. Expand
Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection.
TLDR
Production of cytokines that mainly enhance potentially protective cell-mediated immunity is defective in the women in whom extended HPV infection was observed, and a pronounced shift from type 1 to type 2 cytokine production is associated with more extensive HPV infection. Expand
Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima‐media thickness
TLDR
Inflammatory alterations associated with the genesis of atherosclerotic plaques are detected in otherwise healthy individuals affected by parodontopathy and are positively influenced by periodontal treatment, shedding light on the pathogenesis of Atherosclerosis. Expand
Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonresponders.
TLDR
Hydroxychloroquine reduces lipopolysaccharide/TLR-mediated immune activation; this compound could be a useful immunomodulant in HIV-infected patients. Expand
Cytokine Polymorphisms in the Pathophysiology of Mood Disorders
TLDR
The data support the existence of a genetic profile related to pro-inflammatory cytokines in patients affected by mood disorders and suggest the presence of different pathogenetic mechanisms involved in the susceptibility of phenotypically different mood disorders. Expand
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers.
TLDR
A role is suggested for mucosal HIV-1-specific IgA responses in HIV- 1 resistance, independent of host cellular responses, in Kenyan female sex workers. Expand
Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer’s disease
TLDR
Questions regarding the inflammatory theory in AD are raised, pointing to a pivotal role of IL-10 and IL-6 and a selective alteration in this network. Expand
Cytokine profiles in schizophrenic patients treated with risperidone A 3-month follow-up study
TLDR
Modification of cytokines values suggests that clinical improvement is associated with a reduction in the inflammatory-like situation present in not currently treated schizophrenic patients. Expand
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