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MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions.
- R. Gillitzer, K. Wolff, R. Berger
- Medicine, BiologyThe Journal of investigative dermatology
- 1 August 1993
The strongest MCP-1 message in psoriatic lesions is found above the dermal-epidermal junction and this may explain the characteristic sub-basal distribution of dermal macrophages.
Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts.
- D. Hu, B. Sires, D. Tong, G. A. Royack, D. Oda
- Medicine, BiologyOphthalmic plastic and reconstructive surgery
- 1 March 2000
Short MMC exposure times have a variable cytotoxic effect and inhibit proliferation of cultured nasal mucosa fibroblasts and MMC also can induce apoptosis with a 5-minute exposure time, suggesting that MMC has a complex effect in dacryocystorhinostomy.
Response of human oral epithelial cells to oxidative damage and the effect of vitamin E.
5-Fluorouracil-induced apoptosis in cultured oral cancer cells.
H2O2 oxidative damage in cultured oral epithelial cells: the effect of short-term vitamin C exposure.
It is suggested that H2O2 is capable of altering the cell cycle and morphology of cultured normal human oral epithelial cells, and forty-eight hour exposure to Vitamin C does not prevent thecell cycle changes caused by hydroxyl radicals.
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival
It is reported here that resting, previously antigen-stimulated CD4 T cells maintain a minimalist response to dendritic cells after their peak activation in vitro, and this subtle activation event may be induced by DCs without overt presence of antigen and appears to be stronger if IL-2 comes from the same dendrite cells.
The synergistic antitumor activity of arsenic trioxide and vitamin K2 in HL-60 cells involves increased ROS generation and regulation of the ROS-dependent MAPK signaling pathway.
The results suggest that ATO and VK2 act synergistically to increase HL-60 cell apoptosis, through ROS generation and regulation of the MAPK signaling pathway.
IMMUNIZATION OF RATS BY TUMOUR HYBRID CELLS
- D. Tong
- Biology, Medicine
It was discussed that the function of tumour hybrid cells is possibly to stimulate the host immune system and that the tumour hybrids may be used as an immuno-therapeutic agent to destroy the residual tumour cells after surgery or other treatments.
A fibroblast growth factor-like activity secreted by a human B-cell line
MCP-l D 1 RNA Expression in Basal Keratinocytes of Psoriatic Lesions
By immunohistologic analysis, these dermal macrophages were mainly encountered in the papillary dermis and arranged along the rete ridges in close proximity to proliferating keratinocytes.