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Occurrence of N-glycolylmuramic acid in bacterial cell walls. A preliminary survey.
The N-acyl substituent of muramic acid in the cell walls of some species of Actinomycetales and of the related family of Corynebacteriaceae has been studied. The N-glycolyl derivative, recentlyExpand
Gas chromatography-mass spectrometry method for determination of phospholipid peroxides; I. Transesterification to form methyl esters.
The purpose of this study is to develop methods for determining the chemical species of lipid peroxides that occur in various types of tissue pathology and it appears that the approach of singlet oxygen is strongly inhibited in the sterically hindered region near the phospholipid head groups. Expand
Identification of metabolites from salts of pyridine-2-thiol-1-oxide following intravenous and dermal adminstration to swine.
Chromatographic evidence indicated that the major metabolites were 2,2′-pyridyldisulfide and 2-(pyridyl-N-oxide) sulfonic acid. Expand
Gas chromatography-mass spectrometry method for determination of phospholipid peroxides; II. Transesterification to form pentafluorobenzyl esters and detection with picogram sensitivity.
A method to prepare pentafluorobenzyl esters of fatty acids and hydroxy fatty acids directly from phospholipids by transesterification at room temperature or from triglycerides at 60 degrees C is presented. Expand
Transesterification of phospholipids or triglycerides to fatty acid benzyl esters with simultaneous methylation of free fatty acids for gas-liquid chromatographic analysis.
A novel method is presented for transesterification of fatty acid esters in phospholipids and triglycerides to benzyl esters while simultaneously recovering free fatty acids as methyl esters, applicable to the formation of esters optimized for detection by absorbance or fluorescence, electron capture, or negative ion chemical ionization. Expand
Metabolic disposition of chlorambucil in rats.
Spontaneous degradation products of [14C]chlorambucil were analysed and compared with the metabolites and most metabolites had undergone oxidation on the butyric acid side-chain to form phenylacetic acid and benzoic acid derivatives. Expand
Characterization and analysis of biphalin: an opioid peptide with a palindromic sequence.
Successful application of nonconventional techniques to characterize and analyze a structurally modified peptide, biphalin, when standard techniques for peptide analysis are inadequate is illustrated. Expand
Occurrence of 4-hydroxyalkenals in rat tissues determined as pentafluorobenzyl oxime derivatives by gas chromatography-mass spectrometry.
The method accomplishes a facile extraction of 4-hydroxynonenal from tissues by forming pentafluorobenzyl oxime derivatives to displace aldehydes from Schiff base linkages. Expand
Acylglucoses of the corynebacteria and mycobacteria.
Mass spectrometry of the methylated lipids and other methylation studies and periodate oxidation indicate that the fatty acids of the acylglucose are esterified to position 6 of the glucose. Expand