D. Thomas

Publications78
h-index44
Citations9,437
Highly Influential Citations375
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Genetic epidemiology of hepatitis C virus throughout egypt.
TLDR
Analysis of genetic distance between isolates was consistent with the introduction of multiple virus strains 75-140 years ago, and no clustering was detected within geographic regions, suggesting widespread dispersion at some time since then.
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Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TLDR
The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.
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The natural history of hepatitis C virus infection: host, viral, and environmental factors.
TLDR
The results indicate that although HCV infection can be self-limited or associated with ESLD, the majority of adults have persistent viremia without clinically demonstrable liver disease.
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Prevalence of Type 2 Diabetes Mellitus among Persons with Hepatitis C Virus Infection in the United States
TLDR
The hypothesis that persons with HCV infection have an increased prevalence of type 2 diabetes after adjustment for important confounding variables, including age, body mass index, poverty level, and history of drug and alcohol use is tested.
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Seroreactivity to hepatitis E virus in areas where the disease is not endemic
If the occurrence of hepatitis E virus antibody (anti-HEV) in regions where the disease is not endemic represents infection, rates may be greater in high-risk populations and behavioral correlates…
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Hepatitis C virus (HCV) infection in a community in the nile delta: Population description and HCV prevalence
TLDR
This study, the largest community‐based survey to date, supports earlier reports of high levels of anti‐HCV among adults in rural areas of Egypt, although many of those who are seropositive will not have active liver disease.
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Hepatitis C virus infection and incident type 2 diabetes
TLDR
Pre‐existing HCV infection may increase the risk for type 2 diabetes in persons with recognized diabetes risk factors, and additional larger prospective evaluations are needed to confirm these preliminary findings.
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Prevalence and incidence of hepatitis C virus infection among young adult injection drug users.
TLDR
The need for wider legal access to sterile syringes, as well as expanded community outreach education to this population of young adult injection drug users, is supported to prevent transmission of HCV.
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Vaccines to prevent viral hepatitis.
  • S. Lemon, D. Thomas
  • Medicine, Biology
    The New England journal of medicine
  • 16 January 1997
At least five different viruses cause hepatitis in humans. Two — hepatitis A virus (HAV) and hepatitis E virus (HEV) — are nonenveloped RNA viruses that are spread predominantly by fecal–oral…
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Racial differences in HLA class II associations with hepatitis C virus outcomes.
TLDR
A role for class II alleles in the immune response to HCV is supported and the importance of studying genetic associations in an ethnically diverse cohort is underscored.
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