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- Publications
- Influence
Management of acne: a report from a Global Alliance to Improve Outcomes in Acne.
- H. Gollnick, W. Cunliffe, +5 authors D. Thiboutot
- Medicine
- Journal of the American Academy of Dermatology
- 1 July 2003
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
- D. Thiboutot, H. Gollnick, +19 authors J. Wolf
- Medicine
- Journal of the American Academy of Dermatology
- 1 May 2009
The Global Alliance to Improve Outcomes in Acne published recommendations for the management of acne as a supplement to the Journal of the American Academy of Dermatology in 2003. The recommendations… Expand
Guidelines of care for acne vulgaris management.
- J. Strauss, D. Krowchuk, +8 authors R. Bhushan
- Medicine
- Journal of the American Academy of Dermatology
- 1 April 2007
DISCLAIMER
Adherence to these guidelines will not ensure successful treatment in every situation. Furthermore, these guidelines should not be deemed inclusive of all proper methods of care or… Expand
Thematic review series: Skin Lipids. Sebaceous gland lipids: friend or foe? Published, JLR Papers in Press, November 1, 2007.
- K. R. Smith, D. Thiboutot
- Biology, Medicine
- Journal of Lipid Research
- 1 February 2008
Sebaceous glands are intriguing glands that are found throughout the human body except on the palms of the hands and soles of the feet. The true function of these glands has yet to be determined, but… Expand
Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee
- R. Gallo, R. Granstein, +4 authors D. Thiboutot
- Medicine
- Journal of the American Academy of Dermatology
- 2018
&NA; In 2002, the National Rosacea Society assembled an expert committee to develop the first standard classification of rosacea. This original classification was intended to be updated as scientific… Expand
Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1).
- D. Thiboutot, S. Jabara, +4 authors G. Clawson
- Biology, Medicine
- The Journal of investigative dermatology
- 1 June 2003
Although the human sebaceous gland can synthesize cholesterol from acetate and can further metabolize steroids such as dehydroepiandrosterone into potent androgens, the de novo production of steroids… Expand
Cutaneous androgen metabolism: basic research and clinical perspectives.
- Wenchieh Chen, D. Thiboutot, C. Zouboulis
- Biology, Medicine
- The Journal of investigative dermatology
- 1 November 2002
The skin, especially the pilosebaceous unit composed of sebaceous glands and hair follicles, can synthesize androgens de novo from cholesterol or by locally converting circulating weaker androgens to… Expand
The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia.
- L. Drake, M. Hordinsky, +21 authors J. Waldstreicher
- Medicine
- Journal of the American Academy of Dermatology
- 1 October 1999
BACKGROUND
Data suggest that androgenetic alopecia is a process dependent on dihydrotestosterone (DHT) and type 2 5alpha-reductase. Finasteride is a type 2 5alpha-reductase inhibitor that has been… Expand
Finasteride in the treatment of men with frontal male pattern hair loss.
- J. Leyden, F. Dunlap, +21 authors J. Waldstreicher
- Medicine
- Journal of the American Academy of Dermatology
- 1 June 1999
BACKGROUND
Finasteride, a specific inhibitor of type II 5alpha-reductase, decreases serum and scalp dihydrotestosterone and has been shown to be effective in men with vertex male pattern hair loss.… Expand
IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway.
- Terry M Smith, K. Gilliland, G. Clawson, D. Thiboutot
- Biology, Medicine
- The Journal of investigative dermatology
- 1 May 2008
Understanding the factors that regulate sebum production is important in identifying therapeutic targets for acne therapy. Insulin and IGF-1 stimulate sebaceous gland lipogenesis. IGF-1 increases… Expand