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Hypervariability of simple sequences as a general source for polymorphic DNA markers.
  • D. Tautz
  • Biology
    Nucleic acids research
  • 25 August 1989
The polymerase chain reaction (PCR) process is used to show that several randomly chosen simple sequence loci with different nucleotide composition and from different species show extensive length polymorphisms.
The genome of the model beetle and pest Tribolium castaneum
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural
The evolutionary origin of orphan genes
De novo evolution out of non-coding genomic regions is emerging as an important additional mechanism for the evolution of new gene functions, which can become relevant for lineage-specific adaptations.
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
A non-radioactive in situ hybridization technique for the localization of RNA in whole mount Drosophila embryos and revealed translational control of the maternally derived hb mRNA, which was difficult to detect by conventional techniques.
Animals in a bacterial world, a new imperative for the life sciences
Recent technological and intellectual advances that have changed thinking about five questions about how have bacteria facilitated the origin and evolution of animals; how do animals and bacteria affect each other’s genomes; how does normal animal development depend on bacterial partners; and how is homeostasis maintained between animals and their symbionts are highlighted.
Comparative evolutionary analysis of rDNA ITS regions in Drosophila.
The internal transcribed spacer of the ribosomal DNA is generally considered to be under low functional constraint, and it is therefore often treated as a typical nonfunctional spacer sequence, but a statistical test suggests that more than half of the spacer is apparently free to diverge and evolves with a rate that is close to the neutral rate of sequence evolution in Drosophila.
Mitochondrial sequence analysis of Salamandra taxa suggests old splits of major lineages and postglacial recolonizations of Central Europe from distinct source populations of Salamandra salamandra
It is suggested that two subpopulations of S. salamandra are remnants of a large homogeneous population that had colonized Central Europe in a previous interglacial period, approximately 500 000 years ago and have maintained their separate genetic identity in their areas.
A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns
It is found that the phylotypic stage does indeed express the oldest transcriptome set and that younger sets are expressed during early and late development, thus faithfully mirroring the hourglass model of morphological divergence.
An evolutionary analysis of orphan genes in Drosophila.
A model suggesting that orphans may be involved in the evolution of adaptive traits, and that slow-evolving orphan genes may be particularly interesting candidate genes for identifying lineage-specific adaptations is proposed.