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Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network.
TLDR
Infants who developed late-onset sepsis had a significantly prolonged hospital stay and were significantly more likely to die than those who were uninfected, especially if they were infected with Gram-negative organisms or fungi. Expand
Temporal and spatial variation of the human microbiota during pregnancy
TLDR
It is suggested that pregnancy outcomes might be predicted by features of the microbiota early in gestation, as well as the potential impact of a persistent, altered postpartum microbiota on maternal health, including outcomes of pregnancies following short interpregnancy intervals. Expand
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
TLDR
Whole-body hypothermia reduces the risk of death or disability in infants with moderate or severe hypoxic-ischemic encephalopathy and causes no increase in major disability among survivors. Expand
Longitudinal Growth of Hospitalized Very Low Birth Weight Infants
TLDR
Appropriate-for-gestational age infants who survived to hospital discharge without developing chronic lung disease, severe intraventricular hemorrhage, necrotizing enterocolitis, or late onset-sepsis gained weight faster than comparable infants with those morbidities. Expand
Trends in neonatal morbidity and mortality for very low birthweight infants.
TLDR
There have been no significant increases in survival without neonatal and long-term morbidity among VLBW infants between 1997 and 2002, and it is speculated that to improve survival without morbidity requires determining, disseminating, and applying best practices using therapies currently available, and also identifying new strategies and interventions. Expand
Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network.
OBJECTIVE Late-onset sepsis (occurring after 3 days of age) is an important problem in very low birth weight (VLBW) infants. To determine the current incidence of late-onset sepsis, risk factors forExpand
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
TLDR
Whole-body hypothermia reduces the risk of death or disability in infants with moderate or severe hypoxic–ischemic encephalopathy and there was no increase in major disability among survivors. Expand
Neonatal hyperbilirubinemia.
Persistent Pulmonary Hypertension of the Newborn in the Era Before Nitric Oxide: Practice Variation and Outcomes
TLDR
Hyperventilation and alkali infusion are not equivalent in their outcomes in neonates with PPHN and Randomized trials are needed to evaluate the role of these common therapies. Expand
Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants
TLDR
Infants with Gram-negative sepsis were likelier to die than those infected by a Gram-positive organism, but the difference was significant only within 3 days after birth, and remains an important cause of neonatal death. Expand
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