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On the imperfect elasticity of lung tissue.
This paper deals with a unifying hypothesis addressed at lung tissue resistance and its responses to neurohumoral and biophysical stimuli. The hypothesis holds that dissipative and elastic processesExpand
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Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells.
The tensegrity hypothesis holds that the cytoskeleton is a structure whose shape is stabilized predominantly by the tensile stresses borne by filamentous structures. Accordingly, cell stiffness mustExpand
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Mechanical behavior in living cells consistent with the tensegrity model
Alternative models of cell mechanics depict the living cell as a simple mechanical continuum, porous filament gel, tensed cortical membrane, or tensegrity network that maintains a stabilizingExpand
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Contribution of intermediate filaments to cell stiffness, stiffening, and growth.
It has been shown previously that intermediate filament (IF) gels in vitro exhibit stiffening at high-applied stress, and it was suggested that this stiffening property of IFs might be important forExpand
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Tensegrity, cellular biophysics, and the mechanics of living systems.
The recent convergence between physics and biology has led many physicists to enter the fields of cell and developmental biology. One of the most exciting areas of interest has been the emergingExpand
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A Tensegrity Structure With Buckling Compression Elements: Application to Cell Mechanics
A tensegrity structure composed of six slender struts interconnected with 24 linearly elastic cables is used as a model of cell deformability. Struts are allowed to buckle under compression and theirExpand
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A prestressed cable network model of the adherent cell cytoskeleton.
A prestressed cable network is used to model the deformability of the adherent cell actin cytoskeleton. The overall and microstructural model geometries and cable mechanical properties were assignedExpand
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Biomechanics of the lung parenchyma: critical roles of collagen and mechanical forces.
The biomechanical properties of connective tissues play fundamental roles in how mechanical interactions of the body with its environment produce physical forces at the cellular level. It is nowExpand
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Cell prestress. II. Contribution of microtubules.
The tensegrity model hypothesizes that cytoskeleton-based microtubules (MTs) carry compression as they balance a portion of cell contractile stress. To test this hypothesis, we used traction forceExpand
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Surface forces in lungs. I. Alveolar surface tension-lung volume relationships.
Alveolar surface tension (gamma)-lung volume relationships were obtained for quasi-static and dynamic lung pressure-volume (PV) histories from measurements of PV curves of liquid- and air-filledExpand
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