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Evaluation of plants used for antimalarial treatment by the Maasai of Kenya.
The results of this preliminary investigation support the traditional knowledge of Maasai herbalists and justify ethnomedical inquiry as a promising method, specifically, in antimalarial therapy, to yield leads for drug discovery.
The Conservation of Medicinal Plants: Global Importance of Medicinal Plants
A large number of plants are used in traditional medical practices, and have been for more than 3000 years, such as in Chinese Traditional Medicine, Ayurvedic Medicine, Unani Medicine, etc., most of which probably exert therapeutic effects and would be proven as such if they were properly evaluated by Western standards.
Natural product drug discovery and development: new perspectives on international collaboration.
A discussion of policies for international collaboration and compensation being implemented by several developed country organizations, and the perspectives on the current developments given by representatives of some of the source countries located in the regions of greatest biodiversity.
Factors in maintaining indigenous knowledge among ethnic communities of Manus Island
Factors in Maintaining Indigenous Knowledge among Ethnic Communities of Manus Island. Economic Botany 59(4):356-365, 2005. Despite the fact that Manus Province is the most geographically isolated
Potential sweetening agents of plant origin. II. field search for sweet-tastingStevia species
Field work in Paraguay, Peru, Colombia and Mexico, including field organoleptic tests and interviews, showed that leaves of no other Stevia species studied possessed a potent sweet taste comparable to that of S. rebaudiana leaves.
Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots.
Most of the isolates demonstrated cytotoxic activity when tested against cultured P-388 cells, with the flavans being more active than the flavones, and certain of these structurally related flavonoids exhibited somewhat selective activities when evaluated with a number of human cancer cell lines.
Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris.
Three novel clerodane diterpenoids, casearvestrins A-C (1-3), displayed promising bioactivity, both in cytotoxicity assays against a panel of tumor cell lines and in antifungal assays via the growth inhibition of Aspergillus niger in a disk diffusion assay.
Potential sweetening agents of plant origin. III. Organoleptic evaluation of Stevia leaf herbarium samples for sweetness.
Fragments of a 62-year-old leaf of S. rebaudiana exhibited a potent and prolonged sensation of sweetness, thereby indicating the stability of its sweet ent-kaurene glycoside constituents to drying, preservation, mounting and storage.
Discovery of terpenoid and phenolic sweeteners from plants
Several plant-derived compounds of the terpenoid and phenolic types have commercial use as sweeteners. In our research program directed toward the discovery of additional sweet compounds of these