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Poly(ε-Caprolactone) Nanocapsules in Carteolol Ophthalmic Delivery
TLDR
Colloidal suspension made of poly(ε-caprolactone) could offer a good opportunity for ophthalmic delivery of drugs, showing that the undesired noncorneal absorption was reduced.
Comparison of Two Fixed Beta-Blocker-Pilocarpine Combinations
TLDR
The carteolol-pilocarpine combination appears as safe and as effective in the medical treatment of primary open-angle glaucoma or ocular hypertension as the timolol 0.5% and pilocarine 2% fixed combination.
Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery.
TLDR
Colloidal suspension made of poly(epsilon-caprolactone) could offer a good opportunity for ophthalmic delivery of drugs, showing that the undesired noncorneal absorption was reduced.
[Arterial vascularization of the rectus medialis and lateralis oculi muscles (author's transl)].
TLDR
The arterial vascularization of the rectus medialis and lateralis oculi muscles was studied in cadaver following the injection of a stable suspension of radiopaque barium sulfate in the internal carotid artery and the main and secondary intrinsic arterial pedicles constitute a very rich anastomotic network.
[Arterial supply to the anterior segment of the eye. Radioanatomical study of a series of 25 human eyes].
TLDR
The vascularization by the anterior ciliary arteries, especially at the level of the inferior and superior rectus muscle, has to be known in order to avoid an anterior segment ischemia following strabismus surgery.
Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927.
TLDR
From 2 hours after dose administration, sezolamide consistently demonstrated a slightly greater decrease in intraocular pressure than MK-927; however, these differences were not statistically significant.
[Nanocapsules of beta-blocking agents: a new drug carrier in ophthalmology. Application to medical treatment of glaucoma in rabbits].
TLDR
A new drug carrier, polycaprolactone nanocapsules, containing betaxolol in the base form produces very interesting therapeutic effects with much lower drug concentrations than that commonly used in aqueous commercial eye drops; thus, systemic and local side effects could be minimized.
[Serous macular detachment of the neuro-epithelium and flumequine].
TLDR
Flumequine (1 200 mg/day) was prescribed as treatment for infection of the urinary tract to three patients with chronic renal failure, who reported positive scotoma three days later, and it is suggested that this drug may be considered responsible for the ocular symptom reported.
[Systemic effects of ophthalmic solutions].
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