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Resveratrol improves health and survival of mice on a high-calorie diet
- J. Baur, K. Pearson, D. Sinclair
- BiologyNature
- 16 November 2006
TLDR
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
- A. Brunet, L. B. Sweeney, M. Greenberg
- BiologyScience
- 26 March 2004
TLDR
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
- K. Howitz, Kevin J. Bitterman, D. Sinclair
- BiologyNature
- 11 September 2003
TLDR
Therapeutic potential of resveratrol: the in vivo evidence
- J. Baur, D. Sinclair
- BiologyNature Reviews Drug Discovery
- 1 June 2006
TLDR
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
- D. Sinclair, L. Guarente
- Biology, MedicineCell
- 26 December 1997
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.
- N. Price, A. Gomes, D. Sinclair
- BiologyCell metabolism
- 2 May 2012
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
- H. Cohen, Christine Miller, D. Sinclair
- BiologyScience
- 16 July 2004
TLDR
Sirtuins in mammals: insights into their biological function.
- Shaday Michán, D. Sinclair
- BiologyThe Biochemical journal
- 15 May 2007
TLDR
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
- J. Milne, P. Lambert, C. Westphal
- BiologyNature
- 29 November 2007
TLDR
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1*
- Kevin J. Bitterman, Rozalyn M. Anderson, H. Cohen, Magda Latorre-Esteves, D. Sinclair
- BiologyThe Journal of Biological Chemistry
- 22 November 2002
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