• Publications
  • Influence
Enterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy.
OBJECTIVES To study the effect of previously administered antibiotics on the antibiotic susceptibility profile of Enterobacter, the factors affecting mortality, and the emergence of antibioticExpand
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Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci.
The advent of transcription profiling technologies has provided researchers with an unprecedented ability to study biological processes. Accordingly, a custom-made Affymetrix GeneChip, constitutingExpand
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Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial
Antimicrobial resistance results in increased morbidity, mortality, and costs of health care. Prevention of the emergence of resistance and the dissemination of resistant microorganisms will reduceExpand
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The most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? Aminoglycoside Resistance Study Groups.
The aminoglycoside resistance mechanisms revealed by two surveys in Europe and other countries have been compared to those revealed in earlier studies. Mechanisms have become more complex in allExpand
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Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center.
The rate of ceftazidime resistance among Klebsiella pneumoniae isolates recovered from patients at the Cleveland Department of Veterans Affairs Medical Center increased from 6% in the first quarterExpand
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Enterococcal bacteremia without endocarditis.
Seventy-four cases of enterococcal bacteremia without endocarditis were reviewed retrospectively for the years 1963 through 1977. Thirty-nine patients had hospital-acquired infection, 27 had seriousExpand
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Inducible, transferable resistance to vancomycin in Enterococcus faecalis A256.
A strain of Enterococcus faecalis (A256) was isolated from the urine of a patient with urinary sepsis and was found to exhibit susceptibilities (micrograms per milliliter) to various glycopeptides asExpand
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Serious Infections Caused by Bacillus Species
Thirty-eight patients with serious infections caused by organisms belonging to the genus Bacillus are described. Our experience, and that reported in the literature, indicates that, in most cases,Expand
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Serogroup-specific epidemiology of Streptococcus pneumoniae: associations with age, sex, and geography in 7,000 episodes of invasive disease.
A study sample of 7,010 episodes of invasive Streptococcus pneumoniae disease was obtained by combining 13 existing datasets. Disease episodes due to each of 12 pneumococcal serogroups (1, 3-9, 14,Expand
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New β‐lactam–β‐lactamase inhibitor combinations in clinical development
  • D. Shlaes
  • Medicine, Biology
  • Annals of the New York Academy of Sciences
  • 1 January 2013
Tazobactam was the most recent β‐lactamase inhibitor to be approved in 1993. Since the approval of piperacillin–tazobactam, the complexity of β‐lactamase–mediated resistance among Gram‐negativeExpand
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