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Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver
BackgroundThe risk of cancer and other degenerative diseases is inversely correlated with consumption of fruits and vegetables. This beneficial effect is mainly attributed to secondary plantExpand
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2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses apoptosis and leads to hyperphosphorylation of p53 in rat hepatocytes.
Inhibition of apoptosis of preneoplastic cells is thought to represent a major mechanism of action of tumor promoters. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most potent promoter of liverExpand
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Drug metabolizing enzyme activities in rat liver epithelial cell lines, hepatocytes and bile duct cells.
P450-dependent mono-oxygenase and conjugating enzyme activities were studied in rat liver epithelial cells (RLEs) and compared to those in hepatocytes and bile duct cells. Various RLE cell lines wereExpand
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The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF.
Flavonoids are dietary antioxidants that may play a role as adjunct nutritional supplements in cancer or during inflammatory disorders. Hypoxia and the transcription factor hypoxia-inducibleExpand
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Lipidpneumonie durch Lipid-haltige Nasensprays und -tropfen
Hintergrund: Im Rahmen der Routineaktualisierung des Deutschen Arzneimittel-Codex/Neues Rezeptur-Formularium (DAC/NRF), Kapitel „Zubereitungen zur Anwendung in der Nase“ sowie der RezepturhinweiseExpand
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Interactions of TCDD with signal transduction and neoplastic development in c-myc transgenic and TGF-alpha transgenic mice.
The environmental pollutant 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) is one of the most potent tumour promoters in rodent liver (Pitot et al. 1980). TCDD enhances the expansion of preneoplasticExpand
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20th International Symposium on Halogenated Environmental Organic Pollutants & POPS
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