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Betaine improves the PCR amplification of GC-rich DNA sequences.
Betaine improves the co-amplification of the two alternatively spliced variants of the prostate-specific membrane antigen mRNA as well as the amplification of the coding cDNA region of c-jun. It isExpand
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Long-term benefit of 5-aminolevulinic acid fluorescence assisted transurethral resection of superficial bladder cancer: 5-year results of a prospective randomized study.
PURPOSE As shown in various studies 5-aminolevulinic acid (ALA) induces fluorescence of malignant and dysplastic bladder tissue and increases tumor detection rates by about 20%. However, data on theExpand
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MRI of prostate cancer at 1.5 and 3.0 T: comparison of image quality in tumor detection and staging.
OBJECTIVE This prospective study was performed to compare the image quality, tumor delineation, and depiction of staging criteria on MRI of prostate cancer at 1.5 and 3.0 T. SUBJECTS AND METHODSExpand
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Complications, urinary continence, and oncologic outcome of 1000 laparoscopic transperitoneal radical prostatectomies-experience at the Charité Hospital Berlin, Campus Mitte.
OBJECTIVES Laparoscopic transperitoneal radical prostatectomy (LRP) is an alternative to open radical prostatectomy, but data based on large populations are not frequently available. This study wasExpand
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Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma.
OBJECTIVES To analyze the excretion of matrix metalloproteinases (MMPs) 2 and 9 in the urine of patients with bladder cancer according to the stage and grade of tumor and to evaluate their diagnosticExpand
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Differential expression of matrix metalloproteinases and their tissue inhibitors in human primary cultured prostatic cells and malignant prostate cell lines
The aim was to investigate the expression of matrix metalloproteinases (MMPs), membrane type MMPs (MT‐MMPs), and their inhibitors (TIMPs) in human primary cultured prostatic cells and malignantExpand
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Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: Diagnostic and prognostic implications
Our aim was to assess the diagnostic accuracy of bone markers in serum of patients with prostate cancer (PCa) for early detection of bone metastases and their usefulness as predictors of PCa‐causedExpand
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Interchangeability of measurements of total and free prostate-specific antigen in serum with 5 frequently used assay combinations: an update.
BACKGROUND The comparability of total and free prostate-specific antigen (tPSA and fPSA) results among commercial PSA assays has been suggested to be improved by calibration to WHO PSA referenceExpand
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Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer.
We compared the plasma DNA concentrations in patients with different prostate cancer (PCa) stages and with benign prostate hyperplasia (BPH) and in healthy persons. Patients with localized cancer hadExpand
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A multicenter clinical trial on the use of complexed prostate specific antigen in low prostate specific antigen concentrations.
PURPOSE The determination of complexed prostate specific antigen (cPSA) has been suggested to be promising for prostate cancer (PCa) diagnosis. In a multicenter trial we evaluate the diagnostic useExpand
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