D. Scherling

Publications24
h-index10
Citations393
Highly Influential Citations7
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BAY X 3702 : NEUROPROTECTANT 5-HT1A AGONIST
  • 41
  • 2
Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine.
  • 87
  • 1
Pharmacokinetics of nisoldipine. III. Biotransformation of nisoldipine in rat, dog, monkey, and man.
After intraduodenal administration of 14C-labelled (+/-) 3-isobutyl-5-methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-pyridine-3,5-dicarboxylate (nisoldipine, Bay k 5552) to rats approx. 68% of the… Expand
  • 31
  • 1
Biotransformation of nimodipine in rat, dog, and monkey.
14C-labelled (+/-) 3-isopropyl5-(2-methoxyethyl)1,4-dihydro-2,6-dimethyl-4- (3-nitrophenyl)-pyridine-3,5-dicarboxylate (nimodipine, Bay e 9736, Nimotop; CAS 66085-59-4) was administered orally to… Expand
  • 23
  • 1
Biotransformation of nifedipine in rat and dog.
Following oral and/or intraduodenal administration, the biotransformation of 14C-labelled nifedipine (dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-pyridine-3, 5-dicarboxylate, Bay a 1040,… Expand
  • 11
  • 1
Prenatal cocaine exposure and childhood psychopathology: a developmental analysis.
  • D. Scherling
  • Psychology, Medicine
  • The American journal of orthopsychiatry
  • 1994
A rising number of children exposed to cocaine in utero are substantially vulnerable to mortality and morbidity expressed in a variety of physical, cognitive, emotional, motor, and social problems.… Expand
  • 28
  • 1
Nimodipine: synthesis and metabolic pathway.
Key step of the synthesis of the calcium antagonistic cerebral vasodilator (+/-) isopropyl-2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (Bay e 9736, nimodipine)… Expand
  • 28
Nitrendipine: identification and synthesis of main metabolites.
(+/-)-Ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (nitrendipine, Bay e 5009) 1, a calcium antagonistic 1,4-dihydropyridine derivative, is currently under… Expand
  • 17
Biotransformation of nitrendipine in rat, dog, and mouse.
14C-Labelled Nitrendipine (Bay e 5009; Baypress, Bayotensin; CAS 39562-70-4) was administered by the oral and intraduodenal route to rats, dogs, and mice (oral dosing only) to elucidate the… Expand
  • 7
Synthese von [14C] Clotrimazol
Clotrimazole is a new antimycotic agent. 14C-labelled Clotrimazole was needed for the investigation of metabolism and pharmacokinetics of the drug in man and animal.… Expand
  • 2