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Immune responses to implants - a review of the implications for the design of immunomodulatory biomaterials.
A key for long-term survival and function of biomaterials is that they do not elicit a detrimental immune response. As biomaterials can have profound impacts on the host immune response the concept… Expand
Effect of immobilized bone morphogenic protein 2 coating of titanium implants on peri-implant bone formation.
- H. Schliephake, A. Aref, D. Scharnweber, S. Bierbaum, S. Roessler, A. Sewing
- Clinical oral implants research
- 1 October 2005
The aim of the present study was to test the hypothesis that immobilization of bone morphogenic protein (BMP2) on the surface of titanium implants can enhance peri-implant bone formation. Ten adult… Expand
Functionalization of dental implant surfaces using adhesion molecules.
- H. Schliephake, D. Scharnweber, M. Dard, A. Sewing, A. Aref, S. Roessler
- Medicine, Materials Science
- Journal of biomedical materials research. Part B…
- 1 April 2005
The aim of the present study was to test the hypothesis that organic coating of titanium screw implants that provides binding sites for integrin receptors can enhance periimplant bone formation. Ten… Expand
Comparison of microfocus- and synchrotron X-ray tomography for the analysis of osteointegration around Ti6Al4V implants.
- R. Bernhardt, D. Scharnweber, +6 authors H. Worch
- Biology, Medicine
- European cells & materials
- 30 June 2004
Micro-computed tomography (microCT) provides quantitative three-dimensional information of bone around titanium implants similar to classical histology. The study, based on an animal model,… Expand
Coating of titanium implants with collagen, RGD peptide and chondroitin sulfate.
- S. Rammelt, T. Illert, S. Bierbaum, D. Scharnweber, H. Zwipp, W. Schneiders
- Medicine, Materials Science
- 1 November 2006
Coating of orthopaedic implants with extracellular bone matrix components was performed to enhance bone healing. Titanium pins of 0.8mm diameter were coated with type I collagen (Ti/Coll), RGD… Expand
Comparison of chemically and pharmaceutically modified titanium and zirconia implant surfaces in dentistry: a study in sheep.
- Jens D Langhoff, K. Voelter, +6 authors B. von Rechenberg
- International journal of oral and maxillofacial…
- 1 December 2008
Advanced surface modifications and materials were tested on the same implant geometry. Six types of dental implants were tested for osseointegration after 2, 4 and 8 weeks in a sheep pelvis model.… Expand
Characterization of oxide layers on Ti6Al4V and titanium by streaming potential and streaming current measurements
Abstract Titanium and titanium alloys (e.g. Ti6Al4V) are increasingly used as medical implant materials in a wide variety of applications. So far, many surface properties of the passive layer… Expand
Increased bone formation around coated implants.
- B. Stadlinger, S. Bierbaum, +5 authors R. Mai
- Journal of clinical periodontology
- 1 August 2009
AIM We hypothesized that coating threaded, sandblasted acid-etched titanium implants with collagen and chondroitin sulphate (CS) increases bone formation and implant stability, compared with uncoated… Expand
Biomechanical comparison of different surface modifications for dental implants.
- S. Ferguson, Jens D Langhoff, +9 authors F. Schlottig
- The International journal of oral & maxillofacial…
PURPOSE A satisfactory clinical outcome in dental implant treatment relies on primary stability for immediate load bearing. While the geometric design of an implant contributes to mechanical… Expand
Functionally graded materials for biomedical applications
Functional gradation is one characteristic feature of living tissue. Bio-inspired materials open new approaches for manufacturing implants for bone replacement. Different routes for new implant… Expand