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Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage
The adoption of Warburg metabolism is critical for the activation of macrophages in response to lipopolysaccharide. Macrophages stimulated with lipopolysaccharide increase their expression ofExpand
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Plasma membrane proteomes of differentially matured dendritic cells identified by LC–MS/MS combined with iTRAQ labelling
Dendritic cells (DCs) play a pivotal role in polarising Th lymphocyte subsets but it is unclear what molecular events occur when DCs generate Th2-type responses. Here, we analysed plasmaExpand
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IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism
IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections, macrophages are an important source of IL-10; however, theExpand
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Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive
The skin provides an important first line of defence and immunological barrier to invasive pathogens, but immune responses must also be regulated to maintain barrier function and ensure tolerance ofExpand
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The cell identity of cytotoxic T lymphocytes
Understanding cytotoxic T cells has been a major focus of immunology research for decades. Proteomic profiling of these cells now brings them into unprecedented and revealing focus.
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PELTIGERALES (ASCOMYCETES LIQUENIZADOS) DEL BOSQUE ALTO ANDINO DEL PARQUE NACIONAL NATURAL TATAMÁ, COLOMBIA
Peltigerales is a segregated order of Lecanorales, contains most of cianoliquenes wealth and diversity is about 1700 species distributed worldwide. However, the diversity of lichen communities in theExpand
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ANGIOSPERMAS NO ARBÓREAS DE UN BOSQUE HÚMEDO TROPICAL EN EL PIEDEMONTE ANDINO-AMAZÓNICO COLOMBIANO
Objectives: To carry out the inventory of the non-arboreal angiosperms of El Caraño forest, located in the Andean-Amazon piedmont of Colombia which includes the list of species, dispersion syndromes,Expand
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Coccocarpia Pers. (Peltigerales − Ascomicetes Liquenizados) en Colombia
Twelve species of Coccocarpia are now recognized with distribution in Colombia ( C. dissecta Swinsc. & Krog, C. domingensis Vain., C. epiphylla (Fee) Kremp., C. erythroxyli (Spreng.) Swinsc. & Krog,Expand
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Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing
BackgroundSchistosoma mansoni cercariae penetrate the skin by releasing excretory/secretory (E/S) products known as 0-3hRP, which are associated with immune modulation through Toll like receptorExpand
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Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection
Keratinocytes constitute the majority of cells in the skin's epidermis, the first line of defence against percutaneous pathogens. Schistosome larvae (cercariae) actively penetrate the epidermis toExpand
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