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Rotenone, Paraquat, and Parkinson’s Disease
Background Mitochondrial dysfunction and oxidative stress are pathophysiologic mechanisms implicated in experimental models and genetic forms of Parkinson’s disease (PD). Certain pesticides mayExpand
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Residential Radon and Risk of Lung Cancer: A Combined Analysis of 7 North American Case-Control Studies
Background: Underground miners exposed to high levels of radon have an excess risk of lung cancer. Residential exposure to radon is at much lower levels, and the risk of lung cancer with residentialExpand
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Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort.
The authors examined the relation between 45 common agricultural pesticides and prostate cancer incidence in a prospective cohort study of 55,332 male pesticide applicators from Iowa and NorthExpand
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Head injury and amyotrophic lateral sclerosis.
Recent data showed that soccer players in Italy had an unusually high risk of amyotrophic lateral sclerosis (ALS) and that repeated head trauma might have contributed to this increase. The authorsExpand
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The Agricultural Health Study.
The Agricultural Health Study, a large prospective cohort study has been initiated in North Carolina and Iowa. The objectives of this study are to: 1) identify and quantify cancer risks among men,Expand
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Association analysis identifies 65 new breast cancer risk loci
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breastExpand
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Cancer Incidence among Glyphosate-Exposed Pesticide Applicators in the Agricultural Health Study
Glyphosate is a broad-spectrum herbicide that is one of the most frequently applied pesticides in the world. Although there has been little consistent evidence of genotoxicity or carcinogenicity fromExpand
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A Combined Analysis of North American Case-Control Studies of Residential Radon and Lung Cancer
Cohort studies have consistently shown underground miners exposed to high levels of radon to be at excess risk of lung cancer, and extrapolations based on those results indicate that residentialExpand
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Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.
Exposure to certain environmental toxicants may be associated with increased risk of developing diabetes. The authors' aim was to investigate the relation between lifetime exposure to specificExpand
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A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study.
We developed a quantitative method to estimate long-term chemical-specific pesticide exposures in a large prospective cohort study of more than 58000 pesticide applicators in North Carolina and Iowa.Expand
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