D. Sackett

Publications420
h-index92
Citations73,779
Highly Influential Citations1,314
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Evidence based medicine: what it is and what it isn't
TLDR
As evidence based medicine continues to evolve and adapt, now is a useful time to refine the discussion of what it is andWhat it is not. Expand
Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine…
TLDR
You are back where you were in the previous article1 on diagnostic tests: in the library studying an article that will guide you in interpreting ventilation-perfusion (V/Q) lung scans. Expand
Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators.
TLDR
Benefit of carotid endarterectomy was greatest among men, patients with recent stroke as the qualifying event, and patients with hemispheric symptoms, and decisions about treatment for patients in this category must take into account recognized risk factors. Expand
Clinical epidemiology : a basic science for clinical medicine
I might have guessed that a book dedicated to "H.L. Mencken, Kurt Vonnegut, Jr., Douglas Adams, and the Emperor's New Clothes" would be fun to read. It was! Readers will sense the authors' enthusiasm… Expand
An assessment of clinically useful measures of the consequences of treatment.
TLDR
The goal is to provide a clear picture of the individual components of the immune system and provide a strategy for individualized treatment of these components according to their Kesslerian importance. Expand
Evidence-based medicine: how to practice and teach EBM: 2nd ed
Users' Guides to the Medical Literature: III. How to Use an Article About a Diagnostic Test: B. What Are the Results and Will They Help Me In Caring for My Patients?
TLDR
The patient is a 28-year-old man whose acute onset of shortness of breath and vague chest pain began shortly after completing a 10-hour auto trip, and the physician is very apprehensive about his symptoms. Expand
Evidence-based medicine. A new approach to teaching the practice of medicine.
TLDR
An important goal of the medical residency program is to educate physicians in the practice of evidence-based medicine, and strategies include a weekly, formal academic half-day for residents devoted to learning the necessary skills. Expand
Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.
TLDR
Carotid endarterectomy is highly beneficial to patients with recent hemispheric and retinal transient ischemic attacks or nondisabling strokes and ipsilateral high-grade stenosis of the internal carotid artery. Expand
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