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Research advances on the multiple uses of Moringa oleifera: A sustainable alternative for socially neglected population.
TLDR
This review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. Expand
Feline Histoplasmosis in Brazil: Clinical and Laboratory Aspects and a Comparative Approach of Published Reports
TLDR
Clinical and epidemiological aspects of three cases of feline histoplasmosis are described and compared them to previously described cases and diagnosis and clinical management in endemic areas should be improved. Expand
Terpinen-4-ol, tyrosol, and β-lapachone as potential antifungals against dimorphic fungi
TLDR
These compounds showed a decrease in MIC when the samples were subjected to osmotic stress, suggesting that the compounds acted on the fungal membrane, and all the compounds were able to reduce the ergosterol content of thefungal strains. Expand
Detection of Candida species resistant to azoles in the microbiota of rheas (Rhea americana): possible implications for human and animal health.
TLDR
It is shown that healthy rheas carry potentially pathogenic Candida species in their gastrointestinal tract, including azole-resistant strains that secrete phospholipases, and are prone to disseminating them in the environment. Expand
Histoplasma capsulatum in planktonic and biofilm forms: in vitro susceptibility to amphotericin B, itraconazole and farnesol.
TLDR
Farnesol showed promising results as an antifungal agent against H. capsulatum and also showed adjuvant action, especially when combined with itraconazole, increasing the fungal susceptibility to this drug. Expand
In vitro inhibitory effect of miltefosine against strains of Histoplasma capsulatum var. capsulatum and Sporothrix spp.
TLDR
It is demonstrated that MIL has an antifungal effect in vitro against two potentially pathogenic fungi and that more studies should be performed in order to evaluate its applicability in vivo. Expand
Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence-related exoenzymes.
TLDR
It can be concluded that farnesol has in vitro inhibitory activity against C. neoformans and C. gattii, but has little impact on the production of the analyzed virulence factors. Expand
Molecular methods for the diagnosis and characterization of Cryptococcus: a review.
TLDR
The accumulation of data generated by molecular methods can have a positive impact on monitoring resistant strains and treating diseases. Expand
Effect of Farnesol on Growth, Ergosterol Biosynthesis, and Cell Permeability in Coccidioides posadasii
TLDR
Due to the high in vitro antifungal activity, this work brings perspectives for the performance of in vivo studies to further elucidate the effects of farnesol on the host cells. Expand
Azole resistance in Candida albicans from animals: Highlights on efflux pump activity and gene overexpression
TLDR
Azole resistance in C. albicans strains from animals is a multifactorial process that involves increased efflux pump activity and the overexpression of different genes, including CDR1 and CDR2. Expand
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