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First 2-Hydroxy-3-Methylbut-3-Enyl Substituted Xanthones Isolated From Plants: Structure Elucidation, Synthesis and Antifungal Activity
Two new 2-hydroxy-3-methylbut-3-enyl substituted xanthones, ( - )-caledol 1 and ( - )-dicaledol 2 were isolated from a dichloromethane extract of the leaves of Calophyllum caledonicum (Clusiaceae).Expand
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Tuning a 96-Well Microtiter Plate Fluorescence-Based Assay to Identify AGE Inhibitors in Crude Plant Extracts
Advanced glycation end-products (AGEs) are involved in the pathogenesis of numerous diseases. Among them, cellular accumulation of AGEs contributes to vascular complications in diabetes. BesidesExpand
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Prenylated xanthones and tocotrienols from Garcinia virgata.
Two xanthones, namely virgataxanthone A and B, have been isolated from the stem bark of Garcinia virgata, together with two formylated tocotrienols and the known delta-tocotrienol, griffipavixanthoneExpand
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6-Acylcoumarins from Mesua racemosa
Abstract Two new 6-acylcoumarins, racemosol 1 and mammea A/AC cyclo F 2 were isolated by fractionation of a leave extract of Mesua racemosa (Planch. ex Triana and Planch.) Kostermans. TheirExpand
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Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
Systemic vitamin E metabolites have been proposed as signaling molecules, but their physiological role is unknown. Here we show, by library screening of potential human vitamin E metabolites, thatExpand
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Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea
Abstract A new isoflavonoid, 5-hydroxy-3-(4-hydroxyphenyl)-8-isopropenyl-8,9-dihydro-4H-furo-[2,3-h]-chromen-4-one named derrisisoflavone G (1), four known prenylated flavanones (2–5), four knownExpand
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Synthesis, Characterization, and Electrochemical Study of Complexes with 4,4′-Bis(Salicylideneimino) Diphenylether and Cobalt(II), Copper(II), Zinc(II), and Cadmium(II)
The 4,4′-bis(salicyleneimino) diphenyl ether is a N2O3 Schiff base but it acts as a tetradentate ligand. Its complexes with cobalt (II), copper(II), zinc(II), and cadmium (II) were characterisedExpand
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Novel cytotoxic 4-phenylfuranocoumarins from Calophyllum dispar.
Eight new 4-phenylfuranocoumarins (1-8) have been isolated from the stem bark and the fruits of Calophyllum dispar, together with three known coumarins. The structures of 1-8 were established byExpand
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Synthesis of 2-hydroxy-3-methylbut-3-enyl substituted coumarins and xanthones as natural products. Application of the Schenck ene reaction of singlet oxygen with ortho-prenylphenol precursors
Application of our original photooxidation–reduction methodology to prenylated dihydroxycoumarin and trihydroxyxanthone compounds led to the corresponding ortho-(2-hydroxy-3-methylbut-3-enyl)phenolExpand
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Multi-grams scale purification of xanthanolides from Xanthium macrocarpum. Centrifugal partition chromatography versus silica gel chromatography.
Plants of the Asteraceae family are known as a source of sesquiterpene lactones with interesting biological activities. The purification of several xanthanolides (xanthathin, 4-epi-xanthanol andExpand
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