OrthoMCL: identification of ortholog groups for eukaryotic genomes.
OrthoMCL provides a scalable method for constructing orthologous groups across multiple eukaryotic taxa, using a Markov Cluster algorithm to group (putative) orthologs and paralogs.
Genome sequence of the human malaria parasite Plasmodium falciparum
The genome sequence of P. falciparum clone 3D7 is reported, which is the most (A + T)-rich genome sequenced to date and is being exploited in the search for new drugs and vaccines to fight malaria.
PlasmoDB: a functional genomic database for malaria parasites
The latest release, PlasmoDB 5.5, contains numerous new data types from several broad categories—annotated genomes, evidence of transcription, proteomics evidence, protein function evidence, population biology and evolution.
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups
The OrthoMCL-DB provides a centralized warehouse for orthology prediction among multiple species, and will be updated and expanded as additional genome sequence data become available.
TriTrypDB: a functional genomic resource for the Trypanosomatidae
TriTrypDB is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs, utilizing a sophisticated search strategy system.
Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups.
This work describes how you can group your proteins of interest into ortholog clusters using two different means provided by the OrthoMCL system.
ToxoDB: an integrated Toxoplasma gondii database resource
ToxoDB has matured significantly since its initial release and the numerous updates with respect to the data and increased functionality available on the website are outlined.
Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii.
Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii
These results provide new markers for the different subcompartments within the apical complex, and revealed previously unknown cellular compartments, which facilitate the understanding of how the invasion machinery is built.
A Plastid of Probable Green Algal Origin in Apicomplexan Parasites
Observations indicate that the Apicomplexa acquired a plastid by secondary endosymbiosis, probably from a green alga.