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OrthoMCL: identification of ortholog groups for eukaryotic genomes.
The identification of orthologous groups is useful for genome annotation, studies on gene/protein evolution, comparative genomics, and the identification of taxonomically restricted sequences.Expand
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Genome sequence of the human malaria parasite Plasmodium falciparum
The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million African children annually. Here we report an analysis of the genomeExpand
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PlasmoDB: a functional genomic database for malaria parasites
PlasmoDB (http://PlasmoDB.org) is a functional genomic database for Plasmodium spp. that provides a resource for data analysis and visualization in a gene-by-gene or genome-wide scale. PlasmoDBExpand
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OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups
TLDR
We cluster proteins based on sequence similarity, using an all-against-all BLAST search of each species' proteome, followed by normalization of inter-species differences, and Markov clustering. Expand
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TriTrypDB: a functional genomic resource for the Trypanosomatidae
TLDR
TriTrypDB (http://tritrypdb.org) is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting complex queries driven by research and development needs. Expand
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ToxoDB: an integrated Toxoplasma gondii database resource
TLDR
ToxoDB is a genome and functional genomic database for the protozoan parasite Toxoplasma gondii. Expand
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Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups.
OrthoMCL is an algorithm for grouping proteins into ortholog groups based on their sequence similarity. OrthoMCL-DB is a public database that allows users to browse and view ortholog groups that wereExpand
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Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii.
Publisher Summary The genetic structure of Toxoplasma gondii is notable chiefly for being relatively conventional— similar to that of its mammalian host cells with respect to gene organization, codonExpand
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A Plastid of Probable Green Algal Origin in Apicomplexan Parasites
Protozoan parasites of the phylum Apicomplexa contain three genetic elements: the nuclear and mitochondrial genomes characteristic of virtually all eukaryotic cells and a 35-kilobase circularExpand
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Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii
The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. TheExpand
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