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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
We revise and renew the “MISEV2014” guidelines for studies of extracellular vesicles based on evolution of the collective knowledge in the last four years. Expand
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A self-tuning DVS processor using delay-error detection and correction
In this paper, we present the implementation and silicon measurements results of a 64bit processor fabricated in 0.18/spl mu/m technology. Expand
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The chemical biology of nitric oxide: implications in cellular signaling.
Nitric oxide (NO) has earned the reputation of being a signaling mediator with many diverse and often opposing biological activities. The diversity in response to this simple diatomic molecule comesExpand
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Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1 (*)
Transforming growth factor-β (TGF-β) is a potent growth regulatory protein secreted by virtually all cells in a latent form. A major mechanism of regulating TGF-β activity occurs through factors thatExpand
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CD47 Is Necessary for Inhibition of Nitric Oxide-stimulated Vascular Cell Responses by Thrombospondin-1*
CD36 is necessary for inhibition of some angiogenic responses by the matricellular glycoprotein thrombospondin-1 and is therefore assumed to be the receptor that mediates its anti-angiogenicExpand
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Many pulmonary pathogenic bacteria bind specifically to the carbohydrate sequence GalNAc beta 1-4Gal found in some glycolipids.
Pneumonia is one of the most common causes of death from infectious disease in the United States. To examine the possible role of carbohydrates as adhesion receptors for infection, several pulmonaryExpand
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Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47*
Thrombospondin-1 (TSP1) can inhibit angiogenic responses directly by interacting with VEGF and indirectly by engaging several endothelial cell TSP1 receptors. We now describe a more potent mechanismExpand
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Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor
Components of the extracellular matrix have been shown to modulate the interaction of endothelial cells with their microenvironment. Here we report that thrombospondin (TSP), an extracellular matrixExpand
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Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner.
Redox signaling plays an important role in the positive regulation of angiogenesis by vascular endothelial growth factor, but its role in signal transduction by angiogenesis inhibitors is less clear.Expand
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Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells.
Thrombospondin 1 (TSP1) inhibits angiogenesis and modulates endothelial cell adhesion, motility, and growth. The antiproliferative activity of TSP1 is mimicked by synthetic peptides derived from theExpand
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