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Correction of anemia with epoetin alfa in chronic kidney disease.
TLDR
The use of a target hemoglobin level of 13.5 g per deciliter (as compared with 11.3 g perDeciliter) was associated with increased risk and no incremental improvement in the quality of life and the use of epoetin alfa targeted to achieve a level of 11.4 g perdeciliter was not associated with an increased risk. Expand
Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes.
TLDR
This study demonstrates that patients achieving their target had better outcomes than those who did not; and among subjects who achieved their randomized target, no increased risk associated with the higher hemoglobin goal was detected. Expand
Association between pulse pressure and mortality in patients undergoing maintenance hemodialysis.
TLDR
Pulse pressure is associated with risk of death in a large, nationally representative sample of patients undergoing maintenance hemodialysis and the recognition of pulse pressure as an important correlate of mortality in patients receiving dialysis highlights the need to investigate the relationship between potential therapeutic implications of conduit vessel function and clinical outcomes in patients with end-stage renal disease. Expand
Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients.
TLDR
Subjects whose systolic blood pressure fell with hemodialysis had a significantly decreased risk of hospitalization or death at 6 months, suggesting that hemodynamic responses to dialysis are associated with short-term outcomes among a group of prevalent he modialysis subjects. Expand
White blood cells as a novel mortality predictor in haemodialysis patients.
TLDR
An increased neutrophil count and reduced lymphocyte count are independent predictors of increased mortality risk in haemodialysis patients. Expand
Intradialytic blood volume monitoring in ambulatory hemodialysis patients: a randomized trial.
TLDR
The atypically low hospitalization and mortality rates for the conventional monitoring group suggest that these findings should be generalized to the US hemodialysis population with caution. Expand
Chronic kidney disease, mortality, and treatment strategies among patients with clinically significant coronary artery disease.
TLDR
Ass associations between CKD, cardiac revascularization strategies, and mortality among patients with CKD and cardiovascular disease are described and CABG is associated with greater mortality reduction than PCI in severe CKD. Expand
Differential survival after coronary revascularization procedures among patients with renal insufficiency.
TLDR
A survival benefit among patients with ESRD undergoing CABG surgery as compared with PCI is demonstrated, while controlling for severity of coronary artery disease, left ventricular dysfunction, and other comorbid conditions. Expand
Contrast-induced nephropathy and its prevention: What do we really know from evidence-based findings?
TLDR
Large, well-designed trials that consider all the complexities involved in CIN and its prevention are needed before the clinical community has the evidence-based direction required for optimized patient care. Expand
Characteristics of treated hypertension in incident hemodialysis and peritoneal dialysis patients.
TLDR
Calcium channel blocker use is widespread among hypertensive dialysis patients and antihypertensive prescription patterns suggest a lack of consensus regarding treatment of hypertension, and results of uncertain clinical significance are revealed. Expand
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