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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- P. Gautret, J. Lagier, +15 authors D. Raoult
- International Journal of Antimicrobial Agents
- 20 March 2020
Hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin, which was significantly more efficient for virus elimination. Expand
Tick-Borne Rickettsioses around the World: Emerging Diseases Challenging Old Concepts
The tick-borne rickettsioses described through 2005 are presented and the epidemiological circumstances that have played a role in the emergence of the newly recognized diseases are focused on. Expand
Molecular identification by
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
It is found that primary resistance to ICIs can be attributed to abnormal gut microbiome composition, and Antibiotics inhibited the clinical benefit of ICIs in patients with advanced cancer. Expand
Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii
Acinetobacter baumannii is a species of nonfermentative gram-negative bacteria commonly found in water and soil. This organism was susceptible to most antibiotics in the 1970s. It has now become a… Expand
Ticks and tickborne bacterial diseases in humans: an emerging infectious threat.
Methods for the detection and isolation of bacteria from ticks are described and advice is given on how tick bites may be prevented and how clinicians should deal with patients who have been bitten by ticks. Expand
Rickettsioses as paradigms of new or emerging infectious diseases
The different steps that resulted in the description of each new rickettsiosis are described and the influence of factors as diverse as physicians' curiosity and the adoption of molecular biology-based identification in helping to recognize these new infections are discussed. Expand
Update on Tick-Borne Rickettsioses around the World: a Geographic Approach
- P. Parola, C. Paddock, +8 authors D. Raoult
- Biology, Medicine
- Clinical Microbiology Reviews
- 1 October 2013
The current knowledge on tick-borne rickettsiae and ricksettsioses is presented using a geographic approach toward the epidemiology of these diseases. Expand
Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
- P. Seng, M. Drancourt, +4 authors D. Raoult
- Clinical infectious diseases : an official…
- 15 August 2009
BACKGROUND Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry accurately identifies both selected bacteria and bacteria in select clinical situations. It has not… Expand
Natural history and pathophysiology of Q fever.
Advances in understanding the pathophysiology and natural history of Q fever are reviewed and the complete genome sequencing of C burnetii is completed. Expand