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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
It is found that primary resistance to ICIs can be attributed to abnormal gut microbiome composition, and Antibiotics inhibited the clinical benefit of ICIs in patients with advanced cancer.
Molecular identification by
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
A key role is revealed for Bacteroidales in the immunostimulatory effects of CTLA-4 blockade, which is found to depend on distinct Bacteroides species in mice and patients.
Update on Tick-Borne Rickettsioses around the World: a Geographic Approach
The current knowledge on tick-borne rickettsiae and ricksettsioses is presented using a geographic approach toward the epidemiology of these diseases.
Tick-Borne Rickettsioses around the World: Emerging Diseases Challenging Old Concepts
The tick-borne rickettsioses described through 2005 are presented and the epidemiological circumstances that have played a role in the emergence of the newly recognized diseases are focused on.
Rickettsioses as paradigms of new or emerging infectious diseases
The different steps that resulted in the description of each new rickettsiosis are described and the influence of factors as diverse as physicians' curiosity and the adoption of molecular biology-based identification in helping to recognize these new infections are discussed.
The 1.2-Megabase Genome Sequence of Mimivirus
The size and complexity of the Mimivirus genome challenge the established frontier between viruses and parasitic cellular organisms and this new sequence data might help shed a new light on the origin of DNA viruses and their role in the early evolution of eukaryotes.
Ticks and tickborne bacterial diseases in humans: an emerging infectious threat.
Methods for the detection and isolation of bacteria from ticks are described and advice is given on how tick bites may be prevented and how clinicians should deal with patients who have been bitten by ticks.
Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii
Acinetobacter baumannii is a species of nonfermentative gram-negative bacteria commonly found in water and soil. This organism was susceptible to most antibiotics in the 1970s. It has now become a…