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Analysis of some heavy metals in the riverine water, sediments and fish from river Ganges at Allahabad
TLDR
The trend of heavy metals accumulation in fish muscles was found to be similar to that observed in sediment and water such as Zn > Pb > Cu > Cr > Cd, respectively. Expand
Carbofuran-induced toxicity in rats: protective role of vitamin C.
TLDR
It is suggested that CF treatment induces OF and OS in the erythrocytes of rats, and pretreatment with vitamin C can mitigate these toxic effects. Expand
λ-cyhalothrin and cypermethrin induced in vivo alterations in the activity of acetylcholinesterase in a freshwater fish, Channa punctatus (Bloch)
TLDR
The findings indicated that apart from the established mechanism of delayed closure of sodium ion channels, these pyrethroids inhibit the activity of AChE in C. punctatus which could further aggravate their neurotoxic effects. Expand
Role of Moringa oleifera in regulation of diabetes-induced oxidative stress.
TLDR
The significant antioxidant activities of M. oleifera leaves from both in vivo as well as in vitro studies suggests that the regular intake of its leaves through diet can protect normal as wellAs diabetic patients against oxidative damage. Expand
Role of Jumonji C-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus.
TLDR
It is concluded that when specific VP1 mutations are displayed, JMJD6 contributes to FMDV infectivity and may be a previously unidentified F MDV receptor. Expand
Carbofuran-Induced Oxidative Stress in Mammalian Brain
TLDR
Rat brain was more severely affected by carbofuran than liver and increased oxidative stress at same pesticide concentrations significantly induced activities of antioxidant enzymes such as superoxide dismutase (SOD) and catalase in rat brain. Expand
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine*
TLDR
The results provide a biochemical explanation for the selection of E138K/M184I in patients who failed combination therapy, and abrogates the polymerase defect of M184I and increases rilpivirine dissociation. Expand
Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity
TLDR
The study shows that obtaining 3Dpol fidelity variants by protein engineering based on polymerase structure and function could be exploited for the development of attenuated FMDV vaccine candidates that are safer and more stable than strains obtained by selective pressure via mutagenic nucleotides or adaptation approaches. Expand
The Roles of Picornavirus Untranslated Regions in Infection and Innate Immunity
TLDR
This review discusses the involvement of 5′- and 3′-terminus UTRs in induction and regulation of host immunity and its consequences for viral life cycle and virulence. Expand
Determination of erythrocyte fragility as a marker of pesticide-induced membrane oxidative damage.
TLDR
Study reveals OF as a potential biomarker of oxidative membraneDamage in pathologic conditions as well as toxicant/xenobiotic/pesticide-induced oxidative membrane damage to erythrocytes. Expand
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