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- Publications
- Influence
Hydroxypropyl methylcellulose acetate succinate-based spray-dried dispersions: an overview.
- D. R. Friesen, Ravi Moysore Shanker, M. Crew, D. T. Smithey, W. Curatolo, J. A. Nightingale
- Medicine, Chemistry
- Molecular pharmaceutics
- 1 December 2008
Spray-dried dispersions (SDDs) of low-solubility drugs have been prepared using the polymer hydroxypropyl methylcellulose acetate succinate (HPMCAS). For a variety of drug structures, these SDDs… Expand
Development of a Biorelevant, Material-Sparing Membrane Flux Test for Rapid Screening of Bioavailability-Enhancing Drug Product Formulations.
- A. M. Stewart, Michael E Grass, D. Mudie, M. Morgen, D. R. Friesen, David T. Vodak
- Chemistry, Medicine
- Molecular pharmaceutics
- 10 May 2017
Bioavailability-enhancing formulations are often used to overcome challenges of poor gastrointestinal solubility for drug substances developed for oral administration. Conventional in vitro… Expand
Hydrogen-permeable metal membranes for high-temperature gas separations
- D. Edlund, D. R. Friesen, B. M. Johnson, W. A. Pledger
- Materials Science
- 1994
Abstract In this paper we describe a composite-metal membrane that shows promise for practical large-scale applications including the manufacture of ethylene, recovery of hydrogen from refinery… Expand
Pharmaceutical compositions containing dispersions of drugs and neutral polymers
- D. R. Friesen, M. Gumkowski, +4 authors J. West
- Chemistry
- 10 May 2002
- 1
- 1
Solid nanocrystalline dispersions of ziprasidone with enhanced bioavailability in the fasted state.
- A. Thombre, W. Caldwell, D. R. Friesen, Scott B. Mccray, S. C. Sutton
- Materials Science, Medicine
- Molecular pharmaceutics
- 30 October 2012
Reducing the absorption difference between fed and fasted states is an important goal in the development of pharmaceutical dosage forms. The goal of this work was to develop and characterize a solid… Expand
Recovery of citric acid from fermentation beer using supported-liquid membranes
- D. R. Friesen, W. C. Babcock, D. Brose, A. Chambers
- Chemistry
- 15 February 1991
Abstract The use of a supported-liquid membrane to separate citric acid from the beer produced by fermentation was studied. The liquid membrane consisted of an organic solution composed of… Expand
Conformational analysis. 7. 1,2-Difluoroethane. An electron-diffraction investigation of the molecular structure, composition, trans-gauche energy and entropy differences, and potential hindering…
- D. R. Friesen, K. Hedberg
- Chemistry
- 1 June 1980
Inhaled PYY(3–36) dry-powder formulation for appetite suppression
- P. Kuehl, Tracey Boyden, +6 authors D. K. Lyon
- Medicine
- Drug development and industrial pharmacy
- 2 January 2016
Abstract Objective: Peptide YY3–36 [PYY(3–36)] has shown efficacy in appetite suppression when dosed by injection modalities (intraperitoneal (IP)/subcutaneous). Transitioning to needle-free… Expand
Conformational analysis. 24. Structure and composition of gaseous oxalyl fluoride, C(2)F(2)O(2): electron-diffraction investigation augmented by data from microwave spectroscopy and molecular orbital…
- D. R. Friesen, Tom R Borgers, L. Hedberg, K. Hedberg
- Chemistry, Medicine
- The journal of physical chemistry. A
- 10 November 2006
The molecular structure and composition of gaseous oxalyl fluoride (OXF) has been investigated by electron diffraction (GED) at nozzle-tip temperatures of -10, 149, and 219 degrees C. The GED data… Expand
Liquid membranes for separating uranium from vanadium and uranium from molybdenum
- W. C. Babcock, D. R. Friesen, E. D. Lachapelle
- Chemistry
- 1 April 1986
Abstract This is the third paper in which we describe the transport of uranium ions through liquid membranes. The subject of this paper is the use of liquid membranes to separate uranium from other… Expand