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Photodynamic therapy - mechanisms, photosensitizers and combinations.
TLDR
The object of this review is the anticancer application of PDT, its advantages and possible modifications to potentiate its effects, and the use of nanoparticles enables achievement a targeted method which is focused on specific receptors, and, as a result, increases the selectivity of the photodynamic therapy. Expand
Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy
TLDR
Within the next few years, probiotic bacteria as well as gut microbiota are likely to become an important component in cancer prevention and treatment. Expand
In Search of Panacea—Review of Recent Studies Concerning Nature-Derived Anticancer Agents
TLDR
The aim of the latest research is to characterize natural compounds found in many common foods, especially by means of their abilities to regulate cell cycle, growth and differentiation, as well as epigenetic modulation. Expand
Effects of Photosensitization of Curcumin in Human Glioblastoma Multiforme Cells
TLDR
CUR is a promising medicament that can be used as a photosensitizer in photodynamic therapy for glioma treatment and over time, its amount decreased and localized in the subcellular compartments. Expand
The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
AbstractNumerous in vitro and in vivo studies have demonstrated the antiproliferative effect of green tea. It has been speculated that one of its compounds — catechin, may affect multidrug resistanceExpand
The favourable effect of catechin in electrochemotherapy in human pancreatic cancer cells.
TLDR
It is found that co-treatment with catechin can firmly enhance the efficacy of electroporation with cisplatin in vitro, which indicates the involvement of the transcriptional-independent mechanisms of cATEchin action. Expand
3PO as a Selective Inhibitor of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 in A375 Human Melanoma Cells
TLDR
3PO presents a dose-dependent and time-independent cytotoxic effect and promotes apoptosis of A375 cells, and the obtained data indicate that 3PO induces cell cycle arrest in G1/0 and glucose uptake reduction. Expand
The Cytoprotective Role of Antioxidants in Mammalian Cells Under Rapidly Varying UV Conditions During Stratospheric Balloon Campaign
TLDR
This study included launching into the stratosphere a balloon containing mammalian normal and cancer cells treated with various compounds to examine whether these substances are capable of protecting the cells against stress caused by rapidly varying temperature, pressure, and radiation, especially UV. Expand
Effects of curcumin based PDT on the viability and the organization of actin in melanotic (A375) and amelanotic melanoma (C32)- in vitro studies.
TLDR
The study demonstrated that PDT induced caspase-3 overexpression and DNA cleavage in the studied cell lines, and cytotoxic effect initiated by curcumin and increased by irradiation confirm the usefulness of the flavonoid in the PDT approach. Expand
Modifications of Plasma Membrane Organization in Cancer Cells for Targeted Therapy
TLDR
In this review, strategies based on cell membrane modulation or reorganization are presented as an alternative tool for future therapeutic protocols. Expand
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