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- Publications
- Influence
The intestinal epithelial stem cell: the mucosal governor
- C. Potten, C. Booth, D. Pritchard
- Biology, Medicine
- International journal of experimental pathology
- 1 August 1997
All epithelial cells in the small and large intestine are thought to originate from stem cells located towards the base of the crypts of Lieberkühn. To‐date, there are no specific intestinal stem… Expand
On the transport of suspended sediment by a swash event on a plane beach
- D. Pritchard, A. Hogg
- Geology
- 2005
We develop solutions for the transport of suspended sediment by a single swash event following the collapse of a bore on a plane beach, and we investigate the morphodynamical role that such transport… Expand
The effects of hydraulic resistance on dam-break and other shallow inertial flows
- A. Hogg, D. Pritchard
- 25 February 2004
The effects of resistive forces on unsteady shallow flows over rigid horizontal boundaries are investigated theoretically. The dynamics of this type of motion are driven by the streamwise gradient of… Expand
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease
- R. Kiesslich, C. Duckworth, +7 authors A. Watson
- Medicine
- Gut
- 24 November 2011
Objectives Loss of intestinal barrier function plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Shedding of intestinal epithelial cells is a potential cause of barrier… Expand
American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and…
- D. Ney, D. Adams, +127 authors J. Metzger
- 2003
s Invited for Fourth Annual Workshop on PULMONARY PHYSIOLOGY AND FUNCTlON TESTlNG IN SMALL LABORATORY ANI Satellite Conference to the Annual Meeting of the AMERICAN THORACIC SOCIETY
- 119
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Morphological modelling of intertidal mudflats: the role of cross-shore tidal currents
- D. Pritchard, A. Hogg, W. Roberts
- Geology
- 1 July 2002
Abstract We describe a mathematical model of the sediment transport resulting from cross-shore tidal currents on an intertidal mudflat. The model is integrated numerically to determine the long-term… Expand
The management of gastric polyps
- A. Goddard, R. Badreldin, D. Pritchard, M. Walker, B. Warren
- Medicine
- Gut
- 30 July 2010
Background Gastric polyps are important as some have malignant potential. If such polyps are left untreated, gastric cancer may result. The malignant potential depends on the histological type of the… Expand
The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia.
- D. Pritchard, C. Potten, J. Hickman
- Biology, Medicine
- Cancer research
- 1 December 1998
The relationship between acute (<36 h) induction of apoptosis and longer-term (>72 h) intestinal histopathology was systematically investigated in vivo using p53 wild-type (+/+) and null (-/-) mice.… Expand
Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration
- L. E. Wroblewski, P-J M Noble, +6 authors A. Varró
- Biology, Medicine
- Journal of Cell Science
- 15 July 2003
Epithelial cell responses to bacterial infection include induction of matrix metalloproteinase 7 (MMP-7). Here, we identify increased MMP-7 expression in the gastric epithelium in response to the… Expand
Uplift histories from river profiles
- D. Pritchard, G. G. Roberts, N. White, C. Richardson
- Geology
- 1 December 2009
[1] Longitudinal river profiles, where elevation of a river bed is plotted as a function of distance along the river bed, contain information about uplift rate. When a region adjacent to a reference… Expand