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The association of pre-treatment neutrophil to lymphocyte ratio with overall survival in patients with glioblastoma multiforme
Neutrophil–lymphocyte ratio (NLR) is a marker of systemic inflammatory response and its elevation has recently been shown to be a poor prognostic factor in many malignancies including colon, prostate… Expand
Cancer-associated malnutrition, cachexia and sarcopenia: the skeleton in the hospital closet 40 years later
- A. Ryan, D. Power, L. Daly, S. Cushen, É. N. Ní Bhuachalla, C. Prado
- Proceedings of the Nutrition Society
- 20 January 2016
An awareness of the importance of nutritional status in hospital settings began more than 40 years ago. Much has been learned since and has altered care. For the past 40 years several large studies… Expand
The impact of body composition parameters on ipilimumab toxicity and survival in patients with metastatic melanoma
Background:Body composition is an important predictor of drug toxicity and outcome. Ipilimumab (Ipi), a monoclonal antibody used to treat metastatic melanoma, has specific toxicities. No validated… Expand
Impact of body composition parameters on clinical outcomes in patients with metastatic castrate-resistant prostate cancer treated with docetaxel.
BACKGROUND Body composition may influence clinical outcomes of certain chemotherapeutic agents. We examined the prognostic significance of skeletal muscle mass and adipose tissue on docetaxel… Expand
Advanced gastric cancer--slow but steady progress.
Progress in gastric cancer has been slow, but steady. Historically, patients commonly presented with significant disease related co-morbidity and received treatment of marginal benefit but… Expand
Obesity, metabolic syndrome and esophageal adenocarcinoma: epidemiology, etiology and new targets.
BACKGROUND Rates of distal and junctional adenocarcinomas are increasing in Western countries. METHODS Systematic review of epidemiological evidence linking obesity to esophageal adenocarcinoma… Expand
Role of adjuvant therapy after resection of colorectal cancer liver metastases.
Liver resection is the goal of treatment strategies for liver-confined metastatic colorectal cancer. However, after resection the majority of patients will experience recurrence. Chemotherapy seems… Expand
Body Composition by Computed Tomography as a Predictor of Toxicity in Patients With Renal Cell Carcinoma Treated With Sunitinib
Background: Sunitinib is a standard first-line option for metastatic renal cell carcinoma (mRCC). Body composition is a prognostic factor in cancer patients and patients with loss of skeletal muscle… Expand
Barrett Esophagus: Prevalence of Central Adiposity, Metabolic Syndrome, and a Proinflammatory State
Background:Obesity is a risk factor for esophageal adenocarcinoma, with a pathway through inflammation and metaplasia secondary to reflux the dominant hypothesis. The proinflammatory impact of… Expand
Pooled Analysis Safety Profile of Nivolumab and Ipilimumab Combination Therapy in Patients With Advanced Melanoma.
- M. Sznol, P. Ferrucci, +19 authors J. Wolchok
- Journal of clinical oncology : official journal…
- 1 December 2017
Purpose The addition of nivolumab (anti-programmed death-1 antibody) to ipilimumab (anti-cytotoxic T-cell lymphocyte-associated 4 antibody) in patients with advanced melanoma improves antitumor… Expand