Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction.
It is strongly suggested that an antibody to TGF-beta is a promising agent to prevent renal tubular fibrosis and apoptosis in UUO.
Renal damage progresses despite improvement of renal function after relief of unilateral ureteral obstruction in adult rats.
Results suggest that the acute recovery in function may be compromised in the long term by the progressive renal fibrosis which was found and pharmacological intervention at the time of relief of UUO, targeted to fibrotic processes, may contribute to long-term recovery of renal function.
Surgery in disorders of sex development (DSD) with a gender issue: If (why), when, and how?
Laparoscopic surgery in children with ventriculoperitoneal shunts: effect of pneumoperitoneum on intracranial pressure--preliminary experience.
CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking
It is shown that CLIC4-null mouse embryos exhibit impaired renal tubulogenesis, and that retromer- and branched actin-mediated trafficking on early endosome regulates apical delivery during early luminogenesis.
Management of adolescents with congenital adrenal hyperplasia.
Guidelines for the Development of Comprehensive Care Centers for Congenital Adrenal Hyperplasia: Guidance from the CARES Foundation Initiative
- R. Auchus, S. Witchel, A. Zuckerman
- MedicineInternational Journal of Pediatric Endocrinology
- 11 November 2010
This document should serve as a "roadmap" for the development phases of comprehensive care centers (CCC) for individuals and families affected by CAH.
Laser tissue welding.
Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction.
- A. Miyajima, J. Chen, D. Poppas, E. Vaughan, D. Felsen
- Biology, MedicineKidney International
- 1 April 2001
It is suggested that mechanical stretch is related to renal tubular apoptosis and that NO plays a protective role in this system in UUO.
Congenital adrenal hyperplasia patient perception of ‘disorders of sex development’ nomenclature
- K. Lin-Su, O. Lekarev, D. Poppas, M. Vogiatzi
- Medicine, PsychologyInternational Journal of Pediatric Endocrinology
- 16 March 2015
The results indicate that the majority of parents and patients with CAH are dissatisfied with the term DSD, and reconsideration of the current nomenclature and ongoing dialogue between the medical community and patients will eventually lead to removal of stigmatization, better management protocols, and improved outcomes.