D. Pla

Publications57
h-index28
Citations2,282
Highly Influential Citations85
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The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
TLDR
It is shown that regulatory components of the venom secretory system may have evolved from a pancreatic origin and that venom toxin genes were co-opted by distinct genomic mechanisms, which provides insight into mechanisms of protein evolution under strong selection.
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Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms
TLDR
Assessment of the venom composition of six related viperid snakes reveals that multiple levels of regulation are responsible for generating variation in venom composition between related snake species, and demonstrates how this variability can undermine the treatment of a neglected tropical disease, snakebite.
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Comparative venomics of the Prairie Rattlesnake (Crotalus viridis viridis) from Colorado: Identification of a novel pattern of ontogenetic changes in venom composition and assessment of the…
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Venomics and antivenomics profiles of North African Cerastes cerastes and C. vipera populations reveals a potentially important therapeutic weakness.
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Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation…
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What killed Karl Patterson Schmidt? Combined venom gland transcriptomic, venomic and antivenomic analysis of the South African green tree snake (the boomslang), Dispholidus typus
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Assessing the preclinical efficacy of antivenoms: from the lethality neutralization assay to antivenomics.
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Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.
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Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids.
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Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: keys to understand the variable immune response in horses.
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