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The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
TLDR
It is shown that regulatory components of the venom secretory system may have evolved from a pancreatic origin and that venom toxin genes were co-opted by distinct genomic mechanisms, which provides insight into mechanisms of protein evolution under strong selection.
Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms
TLDR
Assessment of the venom composition of six related viperid snakes reveals that multiple levels of regulation are responsible for generating variation in venom composition between related snake species, and demonstrates how this variability can undermine the treatment of a neglected tropical disease, snakebite.
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