• Publications
  • Influence
Anionic antimicrobial peptides from eukaryotic organisms.
An overview on current research into AAMPs is presented, which suggests that these peptides are an untapped source of putative antimicrobial agents with novel mechanisms of action and possess potential for application in the medical and biotechnological arenas. Expand
On the selectivity and efficacy of defense peptides with respect to cancer cells
Differences between the anticancer actions of ACPs seem to relate to different levels of interplay between these peptide and membrane‐based factors. Expand
Protein Targeting and Translocation
Part 1 Membrane interaction: biophysics of the membrane interface and its involvement in protein targeting and translocation amphiphilic-helices and lipid interactions signal sequences - initiatorsExpand
Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus.
The photodynamic antibacterial properties of a closely related series of phenothiazinium dyes were tested against several pathogenic strains of Staphylococcus aureus, four of which wereExpand
A study of photobactericidal activity in the phenothiazinium series.
Photodynamic antibacterial properties of a closely related series of commercially available phenothiazinium dyes were tested against a range of pathogenic strains of Gram-positive and Gram-negative organisms, giving up to 100-fold increases in bactericidal activity. Expand
Type II diabetes mellitus and cardiovascular risk factors: Current therapeutic approaches.
Research data suggest that simple strategies combining thiazolidinediones and statins could have complementary effects on CVD risk-factor profiles in diabetes, alongside the ability to control glycemia. Expand
The hydrophobic moment and its use in the classification of amphiphilic structures (Review)
The hydrophobic moment is reviewed and data to query the logic of using a fixed window length and a fixed residue angular periodicity in hydrophobia moment analysis are provided and problems associated with the use of such analysis to predict f -helix structure/function relationships are considered. Expand
Amphiphilic α-Helical Antimicrobial Peptides and Their Structure / Function Relationships
Potential mechanisms by which amphiphilic α-helical antimicrobial peptides are able to disrupt membrane structure and the structural characteristics, which are required for function are discussed. Expand
Antimicrobial Peptides: Their History, Evolution, and Functional Promiscuity
It is known that similarly to prokaryotes, eukaryotes also produce AMPs and, historically, some sources attribute the discovery of eukARYotic AMPs to early work on plants, when in 1896 it was shown that plants without an adaptive immune system remained free from infections. Expand