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Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha.
TLDR
An ER beta-selective antibody that cross-reacts with mouse, rat, and human ER beta protein is reported and its use to determine the distribution of ER beta in the murine brain provides an anatomical framework for understanding the mechanisms by which estrogen regulates specific neural systems in the mouse.
Immunolocalization of estrogen receptor β in the mouse brain: Comparison with estrogen receptor α
TLDR
The development of an ERβ-selective antibody that cross-reacts with mouse, rat, and human ERβ protein and its use to determine the distribution of ERβ in the murine brain is reported.
Origin of luteinizing hormone-releasing hormone neurons
TLDR
It is shown that LHRH neurons originate in the medial olfactory placode of the developing nose, migrate across the nasal septum and enter the forebrain with the nervus terminalis, arching into the septal-preoptic area and hypothalamus.
Assessing the molecular genetics of attention networks
TLDR
The ANT is validated as an endophenotypic assay suitable for assessing how genes influence certain anatomical networks that may be disrupted in various psychiatric disorders and suggests that genetic variation may underlie inter-subject variation in the efficiency of executive attention.
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
TLDR
It is found that an AAV vector containing the LacZ gene resulted in expression of β-galactosidase up to three months post-injection in vivo, and safe and stable TH gene transfer into the denervated striatum may have potential for the genetic therapy of Parkinson's disease.
Stomach ghrelin-secreting cells as food-entrainable circadian clocks
TLDR
It is shown here that ghrelin administration increases locomotor activity in nondeprived animals in the absence of food, and it is concluded that oxyntic gland cells of the stomach contain FEOs, which produce a timed gh Relin output signal that acts widely at both brain and peripheral sites.
Roles of estrogen receptor-alpha gene expression in reproduction-related behaviors in female mice.
TLDR
Findings suggest that ER alpha gene expression plays a key role in female mice, not only for sexual behavior but also for other interrelated behaviors, such as parental and aggressive behaviors.
Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
Estrogen receptor α (ERα) plays a pivotal role in the regulation of food intake and energy expenditure by estrogens. Although it is well documented that a disruption of ERα signaling in ERα knockout
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