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Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies.
The metabolic characteristics of type 2 diabetes, insulin resistance, and diminished insulin secretion are costly to measure directly. To evaluate the utility of several simple indices derived from… Expand
Incidence of diabetes in youth in the United States.
CONTEXT Data on the incidence of diabetes mellitus (DM) among US youth according to racial/ethnic background and DM type are limited. OBJECTIVE To estimate DM incidence in youth aged younger than… Expand
Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective.
OBJECTIVES To review the magnitude, characteristics, and public health importance of type 2 diabetes in North American youth. RESULTS Among 15- to 19-year-old North American Indians, prevalence of… Expand
Comparison of tests for glycated haemoglobin and fasting and two hour plasma glucose concentrations as diagnostic methods for diabetes
Abstract Objective : To compare the ability of tests measuring two hour plasma glucose, fasting plasma glucose, and glycated haemoglobin concentrations in predicting the specific microvascular… Expand
Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis.
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.
- R. Hanson, M. Ehm, +12 authors W. Knowler
- Medicine, Biology
- American journal of human genetics
- 1 October 1998
Genetic factors influence the development of type II diabetes mellitus, but genetic loci for the most common forms of diabetes have not been identified. A genomic scan was conducted to identify loci… Expand
Predictors of Progression From Impaired Glucose Tolerance to NIDDM: An Analysis of Six Prospective Studies
Risk factors associated with the progression from impaired glucose tolerance (IGT) to NIDDM were examined in data from six prospective studies. IGT and NIDDM were defined in all studies by World… Expand
Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships.
Intrauterine exposure to diabetes is associated with an excess of diabetes and obesity in the offspring, but the effects of intrauterine exposure are confounded by genetic factors. To determine the… Expand
Prevalence of Diabetes in U.S. Youth in 2009: The SEARCH for Diabetes in Youth Study
OBJECTIVE To estimate the prevalence of diabetes in U.S. youth aged <20 years in 2009 and to estimate the total number of youth with diabetes in the U.S. by age, race/ethnicity, and diabetes type.… Expand
The natural history of impaired glucose tolerance in the Pima Indians.
- M. Saad, W. Knowler, D. Pettitt, R. Nelson, D. Mott, P. Bennett
- The New England journal of medicine
- 8 December 1988
Among 384 Pima Indians with impaired glucose tolerance according to World Health Organization criteria who were followed for 1.6 to 11.5 years (median, 3.3), non-insulin-dependent diabetes mellitus… Expand