D. Perkel

Publications107
h-index46
Citations8,905
Highly Influential Citations503
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Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus.
1. Whole-cell patch-clamp recordings of excitatory postsynaptic currents (EPSCs) were made from guinea pig hippocampal CA1 pyramidal cells. The sensitivity of paired pulse facilitation (PPF) and EPSC… Expand
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Analysis of excitatory synaptic action in pyramidal cells using whole‐cell recording from rat hippocampal slices.
1. The pharmacological and biophysical properties of excitatory synapses in the CA1 region of the hippocampus were studied using patch electrodes and whole‐cell recording from thin slices. 2.… Expand
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Revised nomenclature for avian telencephalon and some related brainstem nuclei
The standard nomenclature that has been used for many telencephalic and related brainstem structures in birds is based on flawed assumptions of homology to mammals. In particular, the outdated… Expand
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An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
THE phenomenon of long-term potentiation (LTP), a long lasting increase in the strength of synaptic transmission which is due to brief, repetitive activation of excitatory afferent fibres, is one of… Expand
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Excitatory synaptic currents in Purkinje cells
The N-methyl-D-aspartate (NMDA) and non-NMDA classes of glutamate receptor combine in many regions of the central nervous system to form a dual-component excitatory postsynaptic current. Non-NMDA… Expand
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Multiple cell types distinguished by physiological, pharmacological, and anatomic properties in nucleus HVc of the adult zebra finch.
Nucleus HVc of the songbird is a distinct forebrain region that is essential for song production and shows selective responses to complex auditory stimuli. Two neuronal populations within HVc give… Expand
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Avian brains and a new understanding of vertebrate brain evolution
We believe that names have a powerful influence on the experiments we do and the way in which we think. For this reason, and in the light of new evidence about the function and evolution of the… Expand
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A Telencephalic Nucleus Essential for Song Learning Contains Neurons with Physiological Characteristics of Both Striatum and Globus Pallidus
The song system of oscine birds has frequently been presented as a model system for motor learning in vertebrates. This practice has been bolstered by the growing recognition that one part of the… Expand
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Striatal Dopamine Modulates Basal Ganglia Output and Regulates Social Context-Dependent Behavioral Variability through D1 Receptors
Cortico-basal ganglia (BG) circuits are thought to promote the acquisition of motor skills through reinforcement learning. In songbirds, a specialized portion of the BG is responsible for song… Expand
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Evidence for all‐or‐none regulation of neurotransmitter release: implications for long‐term potentiation.
1. We have used the whole‐cell patch‐clamp recording technique to examine the modulation of dual‐component excitatory postsynaptic currents (EPSCs) in CA1 pyramidal cells in guinea‐pig hippocampal… Expand
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